Trends in Meningococcal Disease in the United States Military, 1971–2010
Published Date:Sep 2012
Source:Emerg Infect Dis. 18(9):1430-1437.
Keywords:1971–2010. Emerg Infect Dis [serial On The Internet]. 2012 Sep [date Cited]. Http://dx.doi.org/10.3201/eid1809.120257
Blair PJ. Trends In Meningococcal Disease In The United States Military
History, 20th Century
History, 21st Century
Infectious Disease Epidemiology
Suggested Citation For This Article: Broderick MP
Description:Meningococci have historically caused extensive illness among members of the United States military. Three successive meningococcal vaccine types were used from 1971 through 2010; overall disease incidence dropped by >90% during this period. During 2006-2010, disease incidence of 0.38 (cases per 100,000 person-years) among members of the US military was not significantly different from the incidence of 0.26 among the age-matched US general population. Of the 26 cases in the US military, 5 were fatal, 15 were vaccine failures (e.g., illness in a person who had been vaccinated), and 9 were caused by Neisseria meningitidis serogroup Y. Incidences among 17- to 19-year-old basic trainees and among US Marines were significantly higher than among comparison military populations (p<0.05). No apparent change in epidemiology of meningococcal disease was observed after replacement of quadrivalent polysaccharide vaccine with conjugate vaccine in 2007. The data demonstrate that vaccination with meningococcal vaccine is effective.
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