Peripheral and Central Auditory Dysfunction Induced by Occupational Exposure to Organic Solvents

Details

• Personal Author:
  Fuente A ; Keith RW ; Morata, Thais C. ; Rabinowitz PM ; Slade MD ; Sparer, Judith ; Taylor T
• Description:
  Objective: To examine the effects of solvent exposure on hearing function, through an audiological test battery, in a population not occupationally exposed to high levels of noise. Methods: One hundred ten workers from a coating factory were studied. Jobs at the factory were divided into three different levels of solvent exposure. Hearing status was assessed with a test battery including pure-tone hearing thresholds (0.5-8 kHz), high-frequency hearing thresholds (12 and 16 kHz), and dichotic listening measured through dichotic digits test. Multiple linear regression models were created to explore possible association between solvent exposure and each of the hearing outcomes. Results: Significant associations between solvent exposure and the three hearing outcomes were found. Covariates such as age, gender, race, and ethnicity were also significantly associated with the studied hearing outcomes. Conclusions: Occupational exposure to solvents may induce both peripheral and central auditory dysfunction. The dichotic digits test seems as a sensible tool to detect central auditory dysfunction associated with solvent exposure. Hearing loss prevention programs may use this tool to monitor hearing in solvent-exposed workers. [Description provided by NIOSH]
• Subjects:
  Biochemistry Biological Factors Chemistry Demography Environmental Monitoring Hazardous Substances Health Care Facilities Workforce And Services Hearing Loss Hearing Loss, Noise-Induced Hypersensitivity Manufacturing And Industrial Facilities Occupational Exposure Occupational Health Risk Assessment Risk Factors Safety Sense Organs Solvents

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• Keywords:
  Audiological-testing Auditory-system Biochemical-indicators Biological-effects Biological-factors Biological-systems Chemical-factory-workers Chemical-hypersensitivity Chemical-reactions Demographic-characteristics Exposure-assessment Exposure-levels Exposure-methods Health-hazards Hearing-disorders Hearing-loss Medical-monitoring Occupational-exposure Occupational-health Physiological-effects Risk-factors Statistical-analysis Worker-health

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• ISSN:
  1076-2752
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Connecticut ; Ohio ; OSHA Region 1 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DART - Division of Applied Research and Technology
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  51
• Issue:
  10
• NIOSHTIC Number:
  nn:20035985
• Citation:
  J Occup Environ Med 2009 Oct; 51(10):1202-1211
• Contact Point Address:
  Adrian Fuente, PhD, Escuela de Fonoaudiologia, Facultad de Medicina, Universidad de Chile, Independencia 1027
• Email:
  afuente@med.uchile.cl
• Federal Fiscal Year:
  2010
• Performing Organization:
  Yale University School of Medicine
• Peer Reviewed:
  True
• Start Date:
  20010701
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• End Date:
  20260630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:24c1657964e3a9331614b50d06a661d48a4cb75d465de6b7386f16150f79709fc28bf9c4e7b19e8163dfd06585615c5b315e6debb2cd15ea2dfbe31288d23f07
• Download URL:
  https://stacks.cdc.gov/view/cdc/187621/cdc_187621_DS1.pdf
• File Type:
  [PDF - 404.25 KB ]