Interpreting Longitudinal Spirometry: Weight Gain and Other Factors Affecting the Recognition of Excessive FEV1 Decline

Details

• Personal Author:
  Avashia BH ; Petsonk, Edward L. ; Wang, Mei Lin
• Description:
  Background: Excessive FEV1 loss in an individual or a group can reflect hazardous exposures and development of lung disease. However, multiple factors may affect FEV1 measurements. Methods: Using medical screening data collected in 1884 chemical plant workers between 1973 and 2003, the influence of multiple factors on repeated measurements of FEV1 was examined. Results: The FEV1 level was associated with age, height, race, sex, cigarette smoking, changes in body weight, and spirometer model. After controlling for these factors, longitudinal FEV1 decline averaged 23.8 ml/year for white males; an additional loss of 8.3 ml was associated with one pack-year smoking and 5.4 ml with a one pound weight gain. Depending on the spirometer model, FEV1 differed by up to 95 ml. Conclusions: The study results provide quantitative estimates of the effect of specific factors on FEV1, and should be useful to health professionals in the evaluation of accelerated lung function declines. [Description provided by NIOSH]
• Subjects:
  Environmental Monitoring Hazardous Substances Hypersensitivity Irritants Lung Lung Diseases Manufacturing And Industrial Facilities Occupational Exposure Occupational Health Respiratory Function Tests Respiratory Hypersensitivity Respiratory System Respiratory Tract Diseases Safety Surveys And Questionnaires Workplace

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• Keywords:
  Author Keywords: Mass Screening Chemical-factory-workers Chemical-hypersensitivity Chemical-industry-workers Chemical-manufacturing-industry Excessive FEV1 Decline Exposure-assessment Exposure-levels Exposure-methods Health-hazards Health-surveys Inhalation-studies Longitudinal Data Mixed Model Occupational-exposure Occupational-hazards Occupational-health Occupational-respiratory-disease Pulmonary-disorders Pulmonary-system-disorders Quantitative-analysis Respiratory-function-tests Respiratory-hypersensitivity Respiratory-infections Respiratory-irritants Respiratory-system-disorders Spirometry Statistical-analysis Surveillance Work-analysis Work-environment Worker-health Workplace-studies

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• ISSN:
  0271-3586
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  52
• Issue:
  10
• NIOSHTIC Number:
  nn:20035979
• Citation:
  Am J Ind Med 2009 Oct; 52(10):782-789
• Contact Point Address:
  Edward L. Petsonk, Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Mail Stop H-G900-2,1095 Willowdale Road, Morgantown, WV 26505
• Email:
  elp2@cdc.gov
• Federal Fiscal Year:
  2010
• Peer Reviewed:
  True
• Source Full Name:
  American Journal of Industrial Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:62f718733578aecff6af9dc6586bab71fe43b36d9ce12dfc0090d9b7e5b69d8fba62ab0406b2c2dde32e8ba2dee6ebcc3cc5370ac693c25fd3d01723eeb83ff8
• Download URL:
  https://stacks.cdc.gov/view/cdc/187619/cdc_187619_DS1.pdf
• File Type:
  [PDF - 110.84 KB ]