Nontuberculous Mycobacteria in Household Plumbing as Possible Cause of Chronic Rhinosinusitis

Tichenor, Wellington S.; Thurlow, Jennifer; McNulty, Steven; Brown-Elliott, Barbara A.; Wallace, Richard J.; Falkinham, Joseph O.

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Nontuberculous Mycobacteria in Household Plumbing as Possible Cause of Chronic Rhinosinusitis

Supporting Files Public Domain

Oct 2012
By Tichenor, Wellington S. ; Thurlow, Jennifer ; McNulty, Steven ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Tichenor, Wellington S. ; Thurlow, Jennifer ; McNulty, Steven ; Brown-Elliott, Barbara A. ; Wallace, Richard J. ; Falkinham, Joseph O.
Description:

Symptoms of chronic rhinosinusitis (CRS) often persist despite treatment. Because nontuberculous mycobacteria (NTM) are resistant to commonly used antimicrobial drugs and are found in drinking water that patients may use for sinus irrigation, we investigated whether some CRS patients were infected with NTM in New York, New York, USA, during 2001-2011. Two approaches were chosen: 1) records of NTM-infected CRS patients were reviewed to identify common features of infection and Mycobacterium species; 2) samples from plumbing in households of 8 NTM-infected patients were cultured for NTM presence. In 3 households sampled, M. avium sharing rep-PCR and pulsed field gel electrophoresis fingerprints identified M. avium isolates clonally related to the patients' isolates. We conclude that patients with treatment-resistant CRS may be infected with NTM and should have cultures performed for NTM so appropriate therapy can be instituted. In addition, the results suggest that CRS patients can be infected by NTM in their household plumbing.
Subjects:

Adult Aged Chronic Disease Culture Media Family Characteristics Female Fresh Water Humans Male Middle Aged Mycobacterium Avium Complex Nontuberculous Mycobacteria Rhinitis Sanitary Engineering Sinusitis
Source:

Emerg Infect Dis. 18(10):1612-1617.
Document Type:

Journal Article
Place as Subject:

New York
Location:

North America
Volume:

18
Issue:

10
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:87c883c51be0c286c68821f220f3bffc80f9f91aee1e181285ec19cef3383d7b
Download URL:

https://stacks.cdc.gov/view/cdc/18751/cdc_18751_DS1.pdf
File Type:

[PDF - 193.91 KB ]

File Language:

English

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