Nontuberculous Mycobacteria in Household Plumbing as Possible Cause of Chronic Rhinosinusitis
Published Date:Oct 2012
Source:Emerg Infect Dis. 18(10):1612-1617.
Falkinham JO. Nontuberculous Mycobacteria In Household Plumbing As Possible Cause Of Chronic Rhinosinusitis. Emerg Infect Dis [Internet]. 2012 Oct [date Cited]. Http://dx.doi.org/10.3201/eid1810.120164
Mycobacterium Avium Complex
Mycobacterium Infections, Nontuberculous
Suggested Citation For This Article: Tichenor WS
Description:Symptoms of chronic rhinosinusitis (CRS) often persist despite treatment. Because nontuberculous mycobacteria (NTM) are resistant to commonly used antimicrobial drugs and are found in drinking water that patients may use for sinus irrigation, we investigated whether some CRS patients were infected with NTM in New York, New York, USA, during 2001-2011. Two approaches were chosen: 1) records of NTM-infected CRS patients were reviewed to identify common features of infection and Mycobacterium species; 2) samples from plumbing in households of 8 NTM-infected patients were cultured for NTM presence. In 3 households sampled, M. avium sharing rep-PCR and pulsed field gel electrophoresis fingerprints identified M. avium isolates clonally related to the patients' isolates. We conclude that patients with treatment-resistant CRS may be infected with NTM and should have cultures performed for NTM so appropriate therapy can be instituted. In addition, the results suggest that CRS patients can be infected by NTM in their household plumbing.
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