Antimicrobial Drug Use and Macrolide-Resistant Streptococcus pyogenes, Belgium

Van Heirstraeten, Liesbet; Coenen, Samuel; Lammens, Christine; Hens, Niel; Goossens, Herman; Malhotra-Kumar, Surbhi

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Antimicrobial Drug Use and Macrolide-Resistant Streptococcus pyogenes, Belgium

Sep 2012
By Van Heirstraeten, Liesbet ; Coenen, Samuel ; Lammens, Christine ; ...
Source: Emerg Infect Dis. 18(9):1515-1518.

[PDF-312.48 KB]

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Van Heirstraeten, Liesbet ; Coenen, Samuel ; Lammens, Christine ; Hens, Niel ; Goossens, Herman ; ... More +

Van Heirstraeten, Liesbet ; Coenen, Samuel ; Lammens, Christine ; Hens, Niel ; Goossens, Herman ; Malhotra-Kumar, Surbhi Less -
Description:

In Belgium, decreasing macrolide, lincosamide, streptogramins B, and tetracycline use during 1997-2007 correlated significantly with decreasing macrolide-resistant Streptococcus pyogenes during 1999-2009. Maintaining drug use below a critical threshold corresponded with low-level macrolide-resistant S. pyogenes and an increased number of erm(A)-harboring emm77 S. pyogenes with low fitness costs.
Subjects:

[+]

Anti-Bacterial Agents Antimicrobial Resistance Bacteria Bacterial Proteins Belgium Dispatch Drug Resistance, Bacterial Erm(A) Fitness Costs Group A Streptococcus Humans Inducible Resistance Macrolides Macrolide Use Membrane Proteins Methyltransferases Microbial Sensitivity Tests Streptococcal Infections Streptococcus Pyogenes
Source:

Emerg Infect Dis. 18(9):1515-1518.
Document Type:

Journal Article
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:52ccae39d3f182ee2995c09dca9c6f1368692f032e0b294b3a33dd513711dbee
Download URL:

https://stacks.cdc.gov/view/cdc/18719/cdc_18719_DS1.pdf
File Type:

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