Antimicrobial Drug Use and Macrolide-Resistant Streptococcus pyogenes, Belgium

Van Heirstraeten, Liesbet; Coenen, Samuel; Lammens, Christine; Hens, Niel; Goossens, Herman; Malhotra-Kumar, Surbhi

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Antimicrobial Drug Use and Macrolide-Resistant Streptococcus pyogenes, Belgium

Published Date:

Sep 2012

Source:

Emerg Infect Dis. 18(9):1515-1518.

[PDF-312.48 KB]

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Alternative Title:

Emerg Infect Dis

Personal Author:

Van Heirstraeten, Liesbet ; Coenen, Samuel ; Lammens, Christine ; Hens, Niel ; Goossens, Herman ; ... More ▼

Description:

In Belgium, decreasing macrolide, lincosamide, streptogramins B, and tetracycline use during 1997-2007 correlated significantly with decreasing macrolide-resistant Streptococcus pyogenes during 1999-2009. Maintaining drug use below a critical threshold corresponded with low-level macrolide-resistant S. pyogenes and an increased number of erm(A)-harboring emm77 S. pyogenes with low fitness costs.

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Journal Article

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Emerging Infectious Diseases

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Antimicrobial Drug Use and Macrolide-Resistant Streptococcus pyogenes, Belgium

Antimicrobial Drug Use and Macrolide-Resistant Streptococcus pyogenes, Belgium

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