Antimicrobial Drug Use and Macrolide-Resistant Streptococcus pyogenes, Belgium
Published Date:Sep 2012
Source:Emerg Infect Dis. 18(9):1515-1518.
Drug Resistance, Bacterial
Group A Streptococcus
Microbial Sensitivity Tests
Description:In Belgium, decreasing macrolide, lincosamide, streptogramins B, and tetracycline use during 1997-2007 correlated significantly with decreasing macrolide-resistant Streptococcus pyogenes during 1999-2009. Maintaining drug use below a critical threshold corresponded with low-level macrolide-resistant S. pyogenes and an increased number of erm(A)-harboring emm77 S. pyogenes with low fitness costs.
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