Antimicrobial Drug Use and Macrolide-Resistant Streptococcus pyogenes, Belgium

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Van Heirstraeten, Liesbet ; Coenen, Samuel ; Lammens, Christine ; Hens, Niel ; Goossens, Herman ; Malhotra-Kumar, Surbhi
• Description:
  In Belgium, decreasing macrolide, lincosamide, streptogramins B, and tetracycline use during 1997-2007 correlated significantly with decreasing macrolide-resistant Streptococcus pyogenes during 1999-2009. Maintaining drug use below a critical threshold corresponded with low-level macrolide-resistant S. pyogenes and an increased number of erm(A)-harboring emm77 S. pyogenes with low fitness costs.
• Subjects:
  Anti-Bacterial Agents Antimicrobial Resistance Bacteria Bacterial Proteins Belgium Dispatch Drug Resistance, Bacterial Erm(A) Fitness Costs Group A Streptococcus Humans Inducible Resistance Macrolides Macrolide Use Membrane Proteins Methyltransferases Microbial Sensitivity Tests Streptococcal Infections Streptococcus Pyogenes

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• Source:
  Emerg Infect Dis. 18(9):1515-1518.
• Document Type:
  Journal Article
• Volume:
  18
• Issue:
  9
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:52ccae39d3f182ee2995c09dca9c6f1368692f032e0b294b3a33dd513711dbee
• Download URL:
  https://stacks.cdc.gov/view/cdc/18719/cdc_18719_DS1.pdf
• File Type:
  [PDF - 312.48 KB ]