Human Health Risks of Engineered Nanomaterials

Details

• Personal Author:
  Shvedova A
• Description:
  There are currently hundreds of available consumer products that contain nanoscale materials. Human exposure is, therefore, likely to occur in occupational and environmental settings. Mounting evidence suggests that some nanomaterials exert toxicity in cultured cells or following in vivo exposures, but this is dependent on the physicochemical characteristics of the materials and the dose. This Working Group report summarizes the discussions of an expert scientific panel regarding the gaps in knowledge that impede effective human health risk assessment for nanomaterials, particularly those that are suspended in a gas or liquid and, thus, deposit on skin or in the respiratory tract. In addition to extensive descriptions of material properties, the Group identified as critical research areas: external and internal dose characterization, mechanisms of response, identification of sensitive subpopulations, and the development of screening strategies and technology to support these investigations. Important concepts in defining health risk are reviewed, as are the specific kinds of studies that will quickly reduce the uncertainties in the risk assessment process. [Description provided by NIOSH]
• Subjects:
  Occupational Health Radiation Dosimeters Risk Assessment Safety Skin
• Keywords:
  Analytical-processes Dosimetry Nanotechnology Risk-analysis Skin-exposure
• ISBN:
  9781402094897
• Document Type:
  Text
• Genre:
  Book
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  5-29
• NIOSHTIC Number:
  nn:20035026
• Citation:
  Nanomaterials: risks and benefits. Linkov I, Steevens J, eds. London: Springer, 2009 Jan; :5-29
• Editor(s):
  Linkov I; Steevens J
• Federal Fiscal Year:
  2009
• NORA Priority Area:
  Manufacturing
• Peer Reviewed:
  False
• Source Full Name:
  Nanomaterials: risks and benefits
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:70fd1cd3a1ced7e4435adf5807196f9a2ebaa45b4469e0ca07d023877446cfe6b8cbb62db60ffaa3731b25b0f941d60de4d42d522917fbf858017239b6f056fb
• Download URL:
  https://stacks.cdc.gov/view/cdc/187020/cdc_187020_DS1.pdf
• File Type:
  [PDF - 4.60 MB ]