Epidemiology of and Risk Factors for Pancreatic Cancer

Details

• Personal Author:
  Gold EB
• Description:
  In the United States, incidence of and mortality from pancreatic cancer increased for several decades earlier in this century but have tended to level off in recent years. Rates increase with age and are higher in blacks than in whites and higher in males than in females. No consistent differences by socioeconomic status or by geographic location in the United States have been identified, although international variation and differences in migrants have been observed. Thus, both genetic and environmental factors may be playing significant roles in the development of pancreatic cancer. Cigarette smoking increases the risk of pancreatic cancer, but the strength of this association is much less than for lung cancer or other smoking-related cancers. Epidemiologic studies of the effect of alcohol consumption on pancreatic cancer largely show no relationship, and the results for coffee consumption indicate little, if any, association. Human studies have suggested positive associations with meat consumption and carbohydrate intake and a protective effect of dietary fiber and consumption of fruits and vegetables. Results of a number of occupational studies are suggestive of increased risk associated with some exposures but are not fully consistent. Thus, much progress has been made in the last two decades in identifying risk factors, but much epidemiologic work is needed to identify and reduce putative exposures. [Description provided by NIOSH]
• Subjects:
  Diagnosis Education Epidemiology Neoplasms Occupational Health Public Health Risk Assessment Risk Factors Safety
• Keywords:
  Cancer Cancer-rates Clinical-diagnosis Public-health Risk-factors Statistical-analysis Survival-rate
• ISSN:
  0039-6109
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  California ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  75
• Issue:
  5
• NIOSHTIC Number:
  nn:20032893
• Citation:
  Surg Clin North Am 1995 Oct; 75(5):819-843
• Contact Point Address:
  Ellen B. Gold: Division of Occupational/Environmental Medicine and Epidemiology, School of Medicine, University of California, Davis, USA
• Federal Fiscal Year:
  1996
• Performing Organization:
  University of California - Davis
• Peer Reviewed:
  True
• Start Date:
  19900930
• Source Full Name:
  The Surgical Clinics of North America
• End Date:
  20020929
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:afef4d62054578a95429a1e3e5a0280882c1957e4149b57b7728b005823aca1f98a4dca797c9d7c0da8a411c4cf36306293978d7121f75acf0c59a882f90a9d9
• Download URL:
  https://stacks.cdc.gov/view/cdc/186690/cdc_186690_DS1.pdf
• File Type:
  [PDF - 8.33 MB ]