“Small” Melanomas: Relation of Prognostic Variables to Diameter of Primary Superficial Spreading Melanomas

Details

• Personal Author:
  Bart RS ; Friedman RJ ; Grier WRN ; Kopf AW ; Mintzis MM ; Postel AH ; Rigel DS ; Rodríguez-Sains RS
• Description:
  The prevalence of congenital-nevus-like nevi (CNLN) in a group of 105 adults who had malignant melanoma (MM) was compared with that in a control group of 601 adults not afflicted by MM. Total cutaneous examinations were performed on both groups. The control group presented with complaints other than pigmented lesions. In this series, 10 (9.5%) of the group with MM had clinically diagnosed CNLN 1.5 cm or larger in diameter. These CNLN were not in contiguity with the MM sites. The 9.5% prevalence of CNLN in the group with MM was significantly higher (p < 0.005) than the 2.5% CNLN observed in the control population. None of the patients in either group had large congenital nevocytic nevi (>/=20 cm). In addition, in the group with MM, 5 patients (4.8%) had nevi spili (NS) and 13 (12.4%) had café-au-lait spots (CLS). The prevalence rates for these two types of pigmented lesions were not significantly different from those observed in the nonmelanoma control group (2.3% for NS; 13.8% for CLS). The relative risk for developing MM is 4.1 in people with CNLN compared with those without CNLN, which indicates that these nevi may be markers for individuals prone to develop malignant melanoma. [Description provided by NIOSH]
• Subjects:
  Diagnosis Neoplasms Occupational Health Risk Assessment Risk Factors Safety Skin Skin Diseases
• Keywords:
  Cancer Clinical Diagnosis Clinical Tests Risk Factors Skin Cancer Tumors
• ISSN:
  0148-0812
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  8
• Issue:
  9
• NIOSHTIC Number:
  nn:20061079
• Citation:
  J Dermatol Surg Oncol 1982 Sep; 8(9):765-770
• Federal Fiscal Year:
  1982
• Performing Organization:
  New York University, New York, New York
• Peer Reviewed:
  True
• Start Date:
  19790401
• Source Full Name:
  The Journal of Dermatologic Surgery and Oncology
• End Date:
  19820331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:45d878dd3316e412731d611e28b22944df734d7477193be7f4a8ee7234a5364103347e4000ef04c2156e30a3d8d6f82a31610f32f72b399a84fb66958838b999
• Download URL:
  https://stacks.cdc.gov/view/cdc/224753/cdc_224753_DS1.pdf
• File Type:
  [PDF - 442.60 KB ]