Natural Rubber Latex (NRL) Allergens Are More Often Detected in Dust than Air

Details

• Personal Author:
  Biagini, Raymond E. ; Bledsoe T ; Elliot M ; Lewis, Daniel M. ; Meade J ; Sharifpour S ; Weissman, David N. ; Zhuang Z
• Description:
  Exposure to NRL allergens plays a key role in inducing NRL allergy. We therefore compared the relative abilities of air and dust sampling to detect NRL allergen contamination in a medical facility. High volume area air samples and vacuumed bulk surface dust samples were collected onto Teflon filters in several hospital and clinic settings. Control samples were collected in a vacant office where NRL was not used. NRL allergen levels in saline filter extracts were determined by inhibition of an immunoassay for NRL-specific human IgE (Pharmacia-Upjohn Diagnostics, Uppsala, Sweden). Threshold limit of detection (LCD) for the air and dust samples was determined as the mean level in the vacant office plus 3 standard deviations. Thus, NRL allergen contamination in a medical facility was more often detected by sampling of bulk surface dust than by area air sampling. [Description provided by NIOSH]
• Subjects:
  Antibodies Antigens Dust Hypersensitivity Occupational Exposure Occupational Health Particulate Matter Respiratory System Safety Workplace
• Keywords:
  Allergens Allergic-disorders Allergic-reactions Allergies Antibody-response Dust-analysis Dust-collectors Dust-exposure Dust-inhalation Dust-particles Inhalation-studies Models Occupational-exposure Particle-aerodynamics Respirable-dust Work-environment Worker-health Workers

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• ISSN:
  0892-6638
• Document Type:
  Text
• Genre:
  Abstract or Summary ; Proceedings
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  14
• Issue:
  6
• NIOSHTIC Number:
  nn:20032668
• Citation:
  FASEB J 2000 Apr; 14(6)(Suppl S):A1248
• Federal Fiscal Year:
  2000
• Peer Reviewed:
  False
• Source Full Name:
  The FASEB Journal
• Supplement:
  S
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:8cff9ae430c2662289955e3a7ab40f5bee33487374453a90dd48aafa31762a791d39c82cc9b16aeed2fcba28f48d3a72e6faf2dc821f4348363fad53912c3184
• Download URL:
  https://stacks.cdc.gov/view/cdc/186558/cdc_186558_DS1.pdf
• File Type:
  [PDF - 487.17 KB ]