Mortality of Vermiculite Miners Exposed to Tremolite

Details

• Personal Author:
  Amandus HE ; Armstrong BG ; McDonald AD ; McDonald JC ; Sebastien P ; Wheeler R
• Description:
  Closely similar cohort mortality studies were conducted independently and in parallel by groups from NIOSH and McGill University among past and present employees of a Montana mine and mill where the vermiculite ore is contaminated by amphibole fibres, mainly of the tremolite-actinolite series. The NIOSH cohort consisted of 569 men hired before 1970, while the McGill cohort consisted of 406 men hired before 1963, and men in both cohorts were employed at least 1 year. Exposures were estimated for each man in fibre-years (f-y) from work histories and all available samples of airborne dust tested by governmental agencies or the company since 1956. A man-years analysis against U.S. white male mortality showed increased SMR's from lung cancer and non-malignant respiratory disease (NIOSH:2.15 and 2.46; McGill: 2.45 and 2.55). In relation to exposure, the SMR for lung cancer was estimated to increase 0.6% by NIOSH and 1.1% by McGill with each unit increase in f-y. Mortality from mesothelioma was reported as the underlying cause of death in 2 cases in the NIOSH cohort, and as the underlying or contributing cause of death in 4 cases in the McGill cohort. [Description provided by NIOSH]
• Subjects:
  Dust Epidemiology Lung Lung Diseases Men Minerals Mining Mortality Neoplasms Occupational Health Respiratory System Respiratory Tract Diseases Safety

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• Keywords:
  Fibrous-dusts Humans Lung-cancer Lung-disorders Mine-workers Mineral-processing Miners Mortality-data Mortality-surveys Pulmonary-system-disorders Respiratory-system-disorders Statistical-analysis

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• ISBN:
  0080341853
• ISSN:
  0003-4878
• Publisher:
  Pergamon Press
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  459-467
• Volume:
  32
• NIOSHTIC Number:
  nn:20032649
• Citation:
  Ann Occup Hyg, Inhaled Particles VI 1988 Dec; 32(Suppl 1):459-467
• CAS Registry Number:
  Tremolite (Ca2[(Mg0.9-1Fe0-0.1)4.5-5Al0-0.5](Si7.5-8Al0-0.5)(OH)2O22) (CAS RN 14567-73-8)
• Editor(s):
  Dodgson J; McCallum RI; Bailey MR; Fisher DR
• Federal Fiscal Year:
  1989
• Peer Reviewed:
  True
• Source Full Name:
  Annals of Occupational Hygiene, Inhaled Particles VI
• Supplement:
  1
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:4352bf23129b945782f575273fcf1cb87545560db8efb3a47cb73d1092b529262302e3f63272c4efce0e086728e48f547f557907fc3195d558d0a8fd7cbb5c92
• Download URL:
  https://stacks.cdc.gov/view/cdc/186547/cdc_186547_DS1.pdf
• File Type:
  [PDF - 165.47 KB ]