Temporal Association of Children’s Pesticide Exposure and Agricultural Spraying: Report of a Longitudinal Biological Monitoring Study

Details

• Personal Author:
  Fenske RA ; Fisker AJ ; Jolley L ; Koch D ; Lu C
• Description:
  We measured organophosphorus (OP) pesticide exposures of young children living in an agricultural community over an entire year and evaluated the impact of agricultural spraying on exposure. We also examined the roles of age, sex, parental occupation, and residential proximity to fields. We recruited 44 children (2-5 years old) through a Women, Infants, and Children clinic. We collected urine samples on a biweekly basis over a 21-month period. Each child provided at least 16 urine samples, and most provided 26. We analyzed samples for the dialkylphosphate (DAP) metabolites common to the OP pesticides. DAP concentrations were elevated in months when OP pesticides were sprayed in the region's orchards. The geometric means of dimethyl and diethyl DAPs during spray months were higher than those during nonspray months (p = 0.009 for dimethyl; p = 0.018 for diethyl). Dimethyl DAP geometric means were 0.1 and 0.07 micro mol/L for spray months and nonspray months, respectively (57% difference); diethyl DAP geometric means were 0.49 and 0.35, respectively (40% difference). We also observed differences for sex of the child, with male levels higher than female levels (p = 0.005 for dimethyl; p = 0.046 for diethyl). We observed no differences due to age, parental occupation, or residential proximity to fields. This study reports for the first time the temporal pattern of pesticide exposures over the course of a full year and indicates that pesticide spraying in an agricultural region can increase children's exposure in the absence of parental work contact with pesticides or residential proximity to pesticide-treated farmland [Description provided by NIOSH]
• Subjects:
  Farmers Insecticides Occupational Exposure Occupational Health Organophosphates Safety Urine
• Keywords:
  Biological-monitoring Children Exposure-levels Exposure-limits Occupational-exposure Occupational-hazards Occupational-health Organo-phosphorus-compounds Organo-phosphorus-pesticides Pesticides Pesticides-and-agricultural-chemicals Urinalysis

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• ISSN:
  0091-6765
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 10 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  110
• Issue:
  8
• NIOSHTIC Number:
  nn:20032257
• Citation:
  Environ Health Perspect 2002 Aug; 110(8):829-833
• Contact Point Address:
  C. Lu, Box 357234, University of Washington, Seattle, WA 98195- 7234 USA
• Email:
  calu@u.washington.edu
• Federal Fiscal Year:
  2002
• NORA Priority Area:
  Neurotoxic Disorders ; Neurotoxic Effects
• Performing Organization:
  University of Washington, Seattle, Washington
• Peer Reviewed:
  True
• Start Date:
  19960930
• Source Full Name:
  Environmental Health Perspectives
• End Date:
  20020929
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6361ad50c92cd49f31b305746fefe55c706f61bd2ef36dc6766eebfb61c001bd228bb83b1238610d32e55d618018ca8d6586deace599000537354676ec567bda
• Download URL:
  https://stacks.cdc.gov/view/cdc/186288/cdc_186288_DS1.pdf
• File Type:
  [PDF - 642.95 KB ]