Risk of Laryngeal Cancer by Occupational Chemical Exposure in Turkey

Details

• Personal Author:
  Akpinar-Elci, Muge ; Blair, Austin ; Dosemeci, Mustafa ; Elci, Omur Cinar
• Description:
  Laryngeal cancer is the second most common cancer among men in Turkey. In this hospital based case-control study, we evaluated laryngeal cancer risks from occupational chemical exposures. We analyzed 940 laryngeal cancer cases and 1519 controls. Occupational history, tobacco, and alcohol use and demographic information were obtained by a questionnaire. The job and industries were classified by special seven-digit codes. We calculated odds ratios (ORs) and 95% confidence intervals (CIs) based on a developed exposure matrix for chemicals, including diesel exhaust, gasoline exhaust, polycyclic aromatic hydrocarbons (PAHs), formaldehyde, and solvents. An excess of laryngeal cancer occurred with diesel exhaust (OR = 1.5, 95% CI = 1.3-1.9), gasoline exhaust (OR = 1.6, 95% CI = 1.3-2.0), and PAHs (OR = 1.3, 95% CI = 1.1-1.6). There was a dose-response relationship for these substances with supraglottic cancers (P < 0.000). The PAH association only occurred among those who also had exposure to diesel exhaust. [Description provided by NIOSH]
• Subjects:
  Alcoholic Beverages Demography Formaldehyde Fuel Oils Hydrocarbons Men Neoplasms Occupational Exposure Occupational Health Polycyclic Aromatic Hydrocarbons Respiratory Tract Diseases Risk Assessment Risk Factors Safety Smokers Solvents Surveys And Questionnaires Vehicle Emissions

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• Keywords:
  Alcoholic-beverages Cancer Demographic-characteristics Diesel-exhausts Dose-response Exhaust-gases Formaldehydes Fuels Larynx-cancer Natural-gas Occupational-exposure Polycyclic-aromatic-hydrocarbons Questionnaires Respiratory-system-disorders Risk-analysis Risk-factors Smoking Throat Throat-disorders

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• ISSN:
  1076-2752
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Maryland ; OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  45
• Issue:
  10
• NIOSHTIC Number:
  nn:20032142
• Citation:
  J Occup Environ Med 2003 Oct; 45(10):1100-1106
• Contact Point Address:
  National Institute for Occupational Safety and Health, Division of Respiratory Diseases Studies, Field Studies Branch, MS2800, 1095 Willowdale Road, Morgantown, WV 26505
• Email:
  oae3@cdc.gov
• CAS Registry Number:
  Formaldehyde (CAS RN 50-00-0)
• Federal Fiscal Year:
  2004
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:89b9dfaa7a200a5286ea32107b89f8bc17b49f52aef84222cd8c605be2d02bed89b4f173a4a512f8d89894ed5de3b8d18ec6906ed731b013ef5e3ffcf31bc344
• Download URL:
  https://stacks.cdc.gov/view/cdc/186189/cdc_186189_DS1.pdf
• File Type:
  [PDF - 186.97 KB ]