Capsular Switching in Invasive Neisseria meningitidis, Brazil1

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Castiñeiras, Terezinha M. P. P. ; Barroso, David E. ; Marsh, Jane W. ; Tulenko, Mary M. ; Krauland, Mary G. ; Rebelo, Maria C. ; Harrison, Lee H.
• Description:
  During the 1990s, an epidemic of B:4 Neisseria meningitidis infections affected Brazil. Subsequent increase in C:4 disease suggested B → C capsular switching. This study identified B → C switches within the sequence type 32 complex. Substantial disease related to capsular switching emphasizes the need for surveillance of circulating meningococcal strains to optimize disease control.
• Subjects:
  Adolescent Adult Antigenic Variation Bacterial Capsules Child Child, Preschool Epidemics Female Genotype Humans Infant Male Meningococcal Infections Middle Aged Multilocus Sequence Typing Neisseria Meningitidis, Serogroup B Neisseria Meningitidis, Serogroup C Sequence Analysis, DNA Serotyping Young Adult

  More +
• Source:
  Emerg Infect Dis. 18(8):1336-1338.
• Document Type:
  Journal Article
• Genre:
  Dispatch
• Place as Subject:
  Brazil
• Volume:
  18
• Issue:
  8
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:7eeb46c0de756c6db5e315341f20273921b4e08736a83334ebcb592feb6ddc30
• Download URL:
  https://stacks.cdc.gov/view/cdc/18618/cdc_18618_DS1.pdf
• File Type:
  [PDF - 145.57 KB ]