Capsular Switching in Invasive Neisseria meningitidis, Brazil1
Published Date:Aug 2012
Source:Emerg Infect Dis. 18(8):1336-1338.
Multilocus Sequence Typing
Neisseria Meningitidis, Serogroup B
Neisseria Meningitidis, Serogroup C
Sequence Analysis, DNA
Description:During the 1990s, an epidemic of B:4 Neisseria meningitidis infections affected Brazil. Subsequent increase in C:4 disease suggested B → C capsular switching. This study identified B → C switches within the sequence type 32 complex. Substantial disease related to capsular switching emphasizes the need for surveillance of circulating meningococcal strains to optimize disease control.
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