Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Schwarz, Norbert G. ; Girmann, Mirko ; Randriamampionona, Njary ; Bialonski, Alexandra ; Maus, Deborah ; ... More +
Schwarz, Norbert G. ; Girmann, Mirko ; Randriamampionona, Njary ; Bialonski, Alexandra ; Maus, Deborah ; Krefis, Anne Caroline ; Njarasoa, Christine ; Rajanalison, Jeanne Fleury ; Ramandrisoa, Herly Daniel ; Randriarison, Maurice Lucien ; May, Jürgen ; Schmidt-Chanasit, Jonas ; Rakotozandrindrainy, Raphael Less -
Description:
In October 2009, two-3 months after an outbreak of a febrile disease with joint pain on the eastern coast of Madagascar, we assessed serologic markers for chikungunya virus (CHIKV), dengue virus (DENV), and Rift Valley fever virus (RVFV) in 1,244 pregnant women at 6 locations. In 2 eastern coast towns, IgG seroprevalence against CHIKV was 45% and 23%; IgM seroprevalence was 28% and 5%. IgG seroprevalence against DENV was 17% and 11%. No anti-DENV IgM was detected. At 4 locations, 450-1,300 m high, IgG seroprevalence against CHIKV was 0%-3%, suggesting CHIKV had not spread to higher inland-altitudes. Four women had IgG against RVFV, probably antibodies from a 2008 epidemic. Most (78%) women from coastal locations with CHIKV-specific IgG reported joint pain and stiffness; 21% reported no symptoms. CHIKV infection was significantly associated with high bodyweight. The outbreak was an isolated CHIKV epidemic without relevant DENV co-transmission.
Subject:
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Animals
Antibodies, Viral
Antibody Specificity
Cell Line
Chikungunya Virus
Dengue Virus
Disease Outbreaks
Fever
Humans
Immunoglobulin G
Immunoglobulin M
Research
Seroepidemiologic Studies

Source:
Emerg Infect Dis. 18(11):1780-1786.
Document Type:
Journal Article
Place as Subject:
Madagascar
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:13ee320f4a26c2297741df2b4dacf37eaebe27e533952520d56bc13fa342bbd6
File Type:

Supporting Files

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