Heart disease mortality among bridge and tunnel officers exposed to carbon monoxide.

Details

• Personal Author:
  Halperin, William E. ; Hornung, Richard W. ; McCammon, Charles S. ; Ringenburg VL ; Stern, Frank B.
• Description:
  Heart disease mortality among bridge and tunnel officers occupationally exposed to carbon-monoxide (630080) was examined in a retrospective study of 5,529 subjects employed between 1952 and 1981 at any one of nine New York City water crossings. Among former tunnel officers, there were 61 deaths from arteriosclerotic heart disease, a 35 percent excess risk compared with the New York City population. Examination of the risk of mortality from arteriosclerotic heart disease among tunnel officers in comparison to the less exposed bridge officers using a proportional hazards model indicated no observable association of arteriosclerotic heart disease with length of exposure; there was, however, significant interaction of exposure with age. The elevated risk of arteriosclerotic heart disease among tunnel officers declined after cessation of exposure, with much of the increased risk dissipating within as a little as 5 years. The authors conclude that exposure to carbon-monoxide may be a major factor in arteriosclerotic heart disease mortality; the parallel findings of this study and studies showing the relation of cigarette smoking to cardiovascular mortality suggest that carbon-monoxide may play an important role in the pathophysiology of cardiovascular mortality associated with cigarette smoking. [Description provided by NIOSH]
• Subjects:
  Cardiovascular Diseases Cardiovascular System Environmental Exposure Epidemiology Hazardous Substances Mortality Occupational Health Risk Assessment Risk Factors Safety Smokers Tobacco Products

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• Keywords:
  Author Keywords: Carbon Monoxide Cardiovascular-disease Cardiovascular-system-disease Cigarette-smoking Environmental-exposure Heart Diseases Long-term-exposure Mortality Mortality-rates NIOSH-Author Risk-factors Toxic-gases Tunnel-workers

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• ISSN:
  0002-9262
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  New York ; Ohio ; OSHA Region 2 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  128
• Issue:
  6
• NIOSHTIC Number:
  nn:00185002
• Citation:
  Am J Epidemiol 1988 Dec; 128(6):1276-1288
• Contact Point Address:
  Frank Stern, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, OH 45226
• CAS Registry Number:
  Carbon monoxide (CAS RN 630-08-0)
• Federal Fiscal Year:
  1989
• Peer Reviewed:
  True
• Source Full Name:
  American Journal of Epidemiology
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:1e47b5b49cd38461f635c6e052a4dca6f8582fc28158d48ff14fc81b429e1518eaa9f344a80a0dd23d3443a9c16129ed747fbb4bd75779dff688e3b7caf26250
• Download URL:
  https://stacks.cdc.gov/view/cdc/185694/cdc_185694_DS1.pdf
• File Type:
  [PDF - 759.50 KB ]