Assessing the health effects of potential exposure to PCBs, dioxins, and furans from electrical transformer fires: the Binghamton State Office Building Medical Surveillance Program.

Details

• Personal Author:
  Fitzgerald EF ; Janerich DT ; Melius, James M. ; Standfast SJ ; Youngblood LG
• Description:
  A medical surveillance program for persons potentially exposed to polychlorobiphenyls (PCBs), dibenzo-p-dioxins (PCDDs), and dibenzofurans (PCDFs) from an electrical transformer fire was described. A total of 482 individuals, 84 percent male, potentially exposed to PCBs, PCDDs, and PCDFs from an electrical transformer fire in a Binghamton, New York, office building in 1981 participated in the program. During the fire, about 180 gallons of a dielectric fluid containing 65 percent Aroclor-1254 (11097691) leaked from a transformer. Serum PCB concentrations were determined immediately after and 9 to 12 months (mo) following the fire. A blood screen for 20 biochemical parameters was performed 9 to 12mo after the fire. A total of 450 subjects were interviewed 6 to 12mo after the fire to obtain information about the nature and extent of exposure and sociodemographic characteristics. A total of 147 firemen and other persons who were in the building for 25 hours or more were questioned about symptoms and examined for physical abnormalities after the fire. Mean serum PCB concentrations determined initially and at followup were 6.90 and 6.50 parts per billion, respectively. The mean serum PCB concentrations were positively correlated with extent of reported exposure. Serum PCB concentrations were also significantly correlated with liver enzyme and lipid concentrations; however, initial and followup liver enzyme and lipid concentrations were not significantly correlated with extent of exposure after covariance adjustment. About 50 percent of the subjects examined had skin lesions; however, no cases of chloracne were seen. Of five participants who reported hepatitis or liver problems, four admitted to heavy drinking. The authors conclude that exposure to contaminants from the building did not cause any significant absorption of PCBs or any major short term health effects. [Description provided by NIOSH]
• Subjects:
  Chlorine Compounds Fires Hazardous Substances Occupational Health Polychlorinated Biphenyls Safety Surveys And Questionnaires
• Keywords:
  Electrical-equipment Fire-hazards Health-hazards Medical-screening Medical-surveys NIOSH-Author Organo-chlorine-compounds Polychlorinated-biphenyls Polychlorinated-hydrocarbons
• ISSN:
  0003-9896
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Connecticut ; New York ; Ohio ; OSHA Region 1 ; OSHA Region 2 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  368-376
• Volume:
  41
• Issue:
  6
• NIOSHTIC Number:
  nn:00166345
• Citation:
  Arch Environ Health 1986 Nov; 41(6):368-376
• CAS Registry Number:
  PCB-1254 (CAS RN 11097-69-1)
• Federal Fiscal Year:
  1987
• Peer Reviewed:
  True
• Source Full Name:
  Archives of Environmental Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:64f6856c3e530a47e69bdc3f795fa61d85d1de11cc23da87b8aeaebcf238ceff582e19acd5a7a8aac2671c67864ae2af18e3e1c92220a7c57838c3e67097ab3a
• Download URL:
  https://stacks.cdc.gov/view/cdc/185097/cdc_185097_DS1.pdf
• File Type:
  [PDF - 995.14 KB ]