A case-control study of leukemia at a naval nuclear shipyard.

Details

• Personal Author:
  Beaumont, James J. ; Bioerbaum PJ ; Halperin, William E. ; Landrigan, Philip J. ; Lee, Shio T. ; Murray, William E. Jr. ; Rinsky RA ; Stern, Frank B. ; Waxweiler RA ; Zumwalde, Ralph D.
• Description:
  A case-control analysis among 53 Portsmouth, New Hampshire, Naval Shipyard (SIC-3731) workers who died from leukemia, and 212 matched controls selected from a cohort of 24,545 workers employed at the shipyard was conducted in an attempt to ascertain associations between leukemia and specific exposures and occupations. The shipyard is a large industrial complex involved in designing, manufacturing, overhauling, and refueling of conventional and nuclear naval vessels. Radiation dose histories and detailed work histories by job and shop were evaluated for each worker studied. No statistically significant associations with leukemia were found among workers exposed to ionizing radiation. An increase in the odds ratio for myeloid leukemia was observed among persons who had accumulated a lifetime radiation dose of at least 1.0 roentgen equivalent man (rem). For workers exposed to organic solvents, the odds ratios were elevated for all of the leukemia cell types, but none of the odds ratios reached statistical significance. Statistically significant excess risks of leukemia were noted for electricians and welders. The odds ratio was significantly elevated for all leukemias in electricians, particularly for lymphatic leukemia. The odds ratio was significantly elevated for myeloid leukemias in welders, but not for all leukemias. Results were observed by univariate analysis and conditional logistic regression analysis. [Description provided by NIOSH]
• Subjects:
  Electricity Epidemiology Hematopoietic System Lymphatic System Occupational Health Radiation Safety Ships
• Keywords:
  Author Keywords: Leukemia Electrical-workers Hematopoietic-system Lymphatic-system-disorders Occupational Diseases Radiation Radiation-exposure Shipyard-workers
• ISSN:
  0002-9262
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  California ; Georgia ; New Hampshire ; Ohio ; OSHA Region 1 ; OSHA Region 4 ; OSHA Region 5 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies ; DSDTT - Division of Standards Development and Technology Transfer ; DBBS - Division of Biomedical and Behavioral Sciences
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  123
• Issue:
  6
• NIOSHTIC Number:
  nn:00163151
• Citation:
  Am J Epidemiol 1986 Jun; 123(6):980-992
• Contact Point Address:
  Frank B. Stern, Division of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Health and Safety (NIOSH), 4676 Columbia Parkway, Cincinnati, OH 45226
• Federal Fiscal Year:
  1986
• Peer Reviewed:
  True
• NAICS and SIC Codes:
  3731 - Ship building and repairing - (SIC)
• Source Full Name:
  American Journal of Epidemiology
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:2e94d8552f84abceb71d7f22f7948689c0314962f6dbee13486f77dcca7c6b57c4e50033f82d4a7556dd4f3615a373c78f2146c658aeaf88fa71605084a05be3
• Download URL:
  https://stacks.cdc.gov/view/cdc/184981/cdc_184981_DS1.pdf
• File Type:
  [PDF - 866.26 KB ]