Neurognathostomiasis, a Neglected Parasitosis of the Central Nervous System

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Katchanov, Juri ; Sawanyawisuth, Kittisak ; Chotmongkol, Verajit ; Nawa, Yukifumi
• Description:
  Gnathostomiasis is a foodborne zoonotic helminthic infection caused by the third-stage larvae of Gnathostoma spp. nematodes. The most severe manifestation involves infection of the central nervous system, neurognathostomiasis. Although gnathostomiasis is endemic to Asia and Latin America, almost all neurognathostomiasis cases are reported from Thailand. Despite high rates of illness and death, neurognathostomiasis has received less attention than the more common cutaneous form of gnathostomiasis, possibly because of the apparent geographic confinement of the neurologic infection to 1 country. Recently, however, the disease has been reported in returned travelers in Europe. We reviewed the English-language literature on neurognathostomiasis and analyzed epidemiology and geographic distribution, mode of central nervous system invasion, pathophysiology, clinical features, neuroimaging data, and treatment options. On the basis of epidemiologic data, clinical signs, neuroimaging, and laboratory findings, we propose diagnostic criteria for neurognathostomiasis.
• Subjects:
  Adult Albendazole Animals Anthelmintics Antibodies, Helminth Central Nervous System Enzyme-Linked Immunosorbent Assay Foodborne Diseases Gnathostoma Gnathostomiasis Humans Larva Magnetic Resonance Imaging Neglected Diseases Nervous System Diseases Survival Rate

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• Source:
  Emerg Infect Dis. 17(7):1174-1180.
• Document Type:
  Journal Article
• Place as Subject:
  Europe ; Thailand
• Volume:
  17
• Issue:
  7
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:6b18b394e70d1e6b419ebc7189ec21f059c0602a66fd55f5ed763c16fa50a10e
• Download URL:
  https://stacks.cdc.gov/view/cdc/18480/cdc_18480_DS1.pdf
• File Type:
  [PDF - 322.53 KB ]