Comparison of auditory-evoked potentials and behavioral thresholds in the normal and noise-exposed chinchilla.

Details

• Personal Author:
  Ahroon WA ; Hamernik RP ; Henderson D ; Salvi RJ
• Description:
  Auditory evoked potential thresholds and behavioral thresholds were compared in normal and noise exposed chinchillas. Animals were anesthetized and the left cochleae were destroyed surgically. One week after surgery, behavioral thresholds were obtained using a shock avoidance conditioning paradigm and a modified method of limits. Auditory evoked potential threshold was defined as the point between the highest intensity where the response was absent and the lowest intensity where the response was present. All thresholds were measured to 20 millisecond signals at 0.5, 1, 2, 2.8, 4, 5.6, and 8 kiloHertz (kHz). Measurements were made at various times before and after exposure to continuous noise combined with impulse noise. The audiograms before noise exposure showed close agreement with the average threshold difference across all frequencies. Multiple t-tests showed no significant differences between behavioral and auditory thresholds before noise exposure. Elevations in the 2kHz threshold 1 day after noise exposure ranged from 10 to 35 decibels. Auditory evoked potential and behavioral measures reflected permanent threshold shifts at higher frequencies following noise exposure. The authors conclude that at lower frequencies, auditory evoked potentials can predict behavioral threshold and offer advantages over traditional threshold testing procedures. [Description provided by NIOSH]
• Subjects:
  Animals Behavior Ear Hearing Loss Hearing Loss, Noise-Induced Noise Noise, Occupational Occupational Health Safety Sense Organs
• Keywords:
  Animal Studies Auditory System Author Keywords: Noise Exposure Behavioral Threshold Biological Effects Ears Evoked Response Hearing Loss Hearing Tests Impulse Noise Noise Exposure Noise Levels Sensory Thresholds

  More +
• ISSN:
  0020-6091
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  172-180
• Volume:
  22
• Issue:
  2
• NIOSHTIC Number:
  nn:00140338
• Citation:
  Audiology 1983 Mar; 22(2):172-180
• Contact Point Address:
  Dr. Roger P. Hamernik, Callier Center for Communication Disorders, University of Texas at Dallas, 1966 Inwood Road, Dallas, TX 75235
• Federal Fiscal Year:
  1983
• Performing Organization:
  Upstate Medical Center, Syracuse, New York
• Peer Reviewed:
  True
• Start Date:
  19720501
• Source Full Name:
  Audiology
• End Date:
  19800630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:f27a24e5bde3c4a08924869749ba6524df1599e2629b2f6a9122c8e53754d0eb327493add705fd34ce3c08689ff4bdd8365b356a9ba052b6d50182033e50a0df
• Download URL:
  https://stacks.cdc.gov/view/cdc/184745/cdc_184745_DS1.pdf
• File Type:
  [PDF - 310.59 KB ]