Predicting Risk for Death from MRSA Bacteremia1
Published Date:Jul 2012
Source:Emerg Infect Dis. 18(7):1072-1080.
Aged, 80 And Over
Drug Resistance, Bacterial
Heteroresistant Staphylococcus Aureus
Methicillin-Resistant Staphylococcus Aureus
Microbial Sensitivity Tests
New York City
Predictive Value Of Tests
Vancomycin Intermediate Staphylococcus Aureus
Description:Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is often fatal. To determine predictors of risk for death, we conducted a retrospective cohort study. We examined 699 episodes of MRSA bacteremia involving 603 patients admitted to an academic medical center in New York City during 2002-2007. Data came from chart reviews, hospital databases, and recultured frozen MRSA specimens. Among the 699 episodes, 55 were caused by vancomycin-intermediate resistant S. aureus strains, 55 by heteroresistant vancomycin-intermediate S. aureus strains, and 589 by non-vancomycin-resistant strains; 190 (31.5%) patients died. We used regression risk analysis to quantify the association between clinical correlates and death. We found that older age, residence in a nursing home, severe bacteremia, and organ impairment were independently associated with increased risk for death; consultation with an infectious disease specialist was associated with lower risk for death; and MRSA strain types were not associated with risk for death.
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