Isocyanate-induced pulmonary diseases: a current perspective.

Details

• Personal Author:
  Bernstein IL
• Description:
  The induction of pulmonary disease by isocyanates is reviewed. Three major diisocyanates, 2,4-toluene-diisocyanate (584849) (TDI), hexamethylene-diisocyanate (822060), and methylene-diphenyl-diisocyanate (101688) are considered. Manufacturing processes and concentrations of exposures from them are presented, as are threshold limit values for TDI. Current research on asthma induced by diisocyanates is emphasized. Future monitoring techniques are proposed which could result in early detection and treatment of pulmonary diseases induced by isocyanates. [Description provided by NIOSH]
• Subjects:
  Air Pollutants, Occupational Lung Diseases Occupational Health Respiratory Tract Diseases Safety
• Keywords:
  Air Contamination Allergic Asthma Industrial Chemicals Occupational Medicine Pulmonary System Disorders
• ISSN:
  0091-6749
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  24-31
• Volume:
  70
• Issue:
  1
• NIOSHTIC Number:
  nn:00126417
• Citation:
  J Allergy Clin Immunol 1982 Jul; 70(1):24-31
• Contact Point Address:
  I. Leonard Bernstein, M.D., Division of Immunology, University of Cincinnati Medical Center, 231 Bethesda Ave., Cincinnati, OH 45267
• CAS Registry Number:
  Diphenylmethane diisocyanate (CAS RN 101-68-8) ; Hexamethylene diisocyanate (CAS RN 822-06-0) ; Toluene 2,4-diisocyanate (CAS RN 584-84-9)
• Federal Fiscal Year:
  1982
• Performing Organization:
  University of Cincinnati, Cincinnati, Ohio
• Peer Reviewed:
  True
• Start Date:
  19780701
• Source Full Name:
  Journal of Allergy and Clinical Immunology
• End Date:
  19810630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:1fb238e3e4edf02671cb42e3d68fee9cc2037f7e84065f3154dd1d4383f3f969b0482bd9f15d78ffc0db7ed582bb3d751f13b15aeef5aeb09203342133d4ad4d
• Download URL:
  https://stacks.cdc.gov/view/cdc/184584/cdc_184584_DS1.pdf
• File Type:
  [PDF - 547.29 KB ]