Chemical and statistical studies of contaminants in urban lungs.

Details

• Personal Author:
  Crable JV ; Crouse, William E. ; Sweet, Doris V.
• Description:
  Lungs taken at autopsy from 100 urban residents were studied to determine concentrations of 21 trace metals, dust, free silica (7631869), and hydroxyproline (51354). Medical, occupational and environmental histories were collected so that correlation studies might be performed. The potential value of this data as a baseline for further studies of occupationally diseased lung tissue was assessed by analysis of variance. The personal histories were used as the criteria for classifying the observations (lung concentrations) into groups for the statistical analysis. Analytical data for dust, hydroxyproline, and trace metals were compared to earlier coal miner studies. Dust levels were comparable to miners dust levels, but the dust itself was of a different composition from one group to the other. Free silica mean concentrations were lower by a factor of 10 in the urban group, while no differences were detected in hydroxyproline levels. The magnitude of the significant differences among group means found indicate the potential value of this urban data as a baseline in an analysis of coal miner data. It is considered desirable in future analyses of data for coal miners to be able to make comparisons with controls without consideration of historical factors. [Description provided by NIOSH]
• Subjects:
  Air Pollutants, Occupational Air Pollution, Indoor Coal Coal Mining Lung Lung Diseases Mining Occupational Health Respiratory System Respiratory Tract Diseases Safety

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• Keywords:
  Air-contamination Coal-workers-pneumoconiosis Lung-disorders NIOSH-Author Physiology Pulmonary-system-disorders
• ISSN:
  0002-8894
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DPSE - Division of Physical Sciences and Engineering
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  39
• Issue:
  7
• NIOSHTIC Number:
  nn:00082215
• Citation:
  Am Ind Hyg Assoc J 1978 Jul; 39(7):515-526
• CAS Registry Number:
  L-Hydroxyproline (CAS RN 51-35-4) ; Silica (CAS RN 7631-86-9)
• Federal Fiscal Year:
  1978
• NORA Priority Area:
  Pulmonary System Disorders
• Peer Reviewed:
  True
• Source Full Name:
  American Industrial Hygiene Association Journal
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:714365809091137ae5704120e87ddf86b759204edcc3a7615c85ae314f538b3d0f01c67cf57fbf7fd6c7572335387d4ecf34fe604810b697e26ec360e8176168
• Download URL:
  https://stacks.cdc.gov/view/cdc/184255/cdc_184255_DS1.pdf
• File Type:
  [PDF - 413.11 KB ]