Histopathologic classification of bronchogenic carcinomas among a cohort of workers occupationally exposed to beryllium.

Details

• Personal Author:
  Smith AB ; Suzuki Y
• Description:
  Pathology reports and specimens of 27 respiratory cancer victims were examined. The subjects had been occupationally exposed to beryllium (7440417) for an undetermined length of time. Microscope slides of tumor specimens were reviewed, tumor histology was classified, and smoking histories were determined from clinical records. In 25 of the cases, the primary site of malignancy was the lung: five of these malignancies were epidermoid carcinomas; nine were small cell anaplastic carcinomas; six were adenocarcinoma, bronchogenic type; two were adenocarcinoma, bronchiolar alveolar type; and three were large cell undifferentiated carcinomas. Among the 25 lung cancer patients, 17 were smokers at the time of hospitalization or were former smokers. The authors conclude that their evidence is insufficient to define the types of specific tumors associated with beryllium exposure. [Description provided by NIOSH]
• Subjects:
  Air Pollutants, Occupational Air Pollution, Indoor Carcinogens Mortality Occupational Health Poisoning Respiratory Tract Diseases Safety
• Keywords:
  Air-contamination Carcinogenesis Metallic-poisons Mortality-data NIOSH-Author Respiratory-system-disorders Statistical-analysis
• ISSN:
  0013-9351
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  10-14
• Volume:
  21
• Issue:
  1
• NIOSHTIC Number:
  nn:00093491
• Citation:
  Environ Res 1980 Feb; 21(1):10-14
• CAS Registry Number:
  Beryllium (CAS RN 7440-41-7)
• Federal Fiscal Year:
  1980
• NORA Priority Area:
  Pulmonary System Disorders
• Peer Reviewed:
  True
• Source Full Name:
  Environmental Research
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:90779dc2d246f182ab0143b18ee6128bfdc723dea55b9ccaaa1bb4738037e8b94353590f7ad9213c80ab78a6e1aac9cac18f904ae3a63fdb6bce29cf82e4c6e2
• Download URL:
  https://stacks.cdc.gov/view/cdc/184327/cdc_184327_DS1.pdf
• File Type:
  [PDF - 280.30 KB ]