Mycobacterium tuberculosis Cluster with Developing Drug Resistance, New York, New York, USA, 2003–2009

Perri, Bianca R.; Proops, Douglas; Moonan, Patrick K.; Munsiff, Sonal S.; Kreiswirth, Barry N.; Kurepina, Natalia; Goranson, Christopher; Ahuja, Shama D.

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Mycobacterium tuberculosis Cluster with Developing Drug Resistance, New York, New York, USA, 2003–2009

Supporting Files Public Domain

Mar 2011
By Perri, Bianca R. ; Proops, Douglas ; Moonan, Patrick K. ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Perri, Bianca R. ; Proops, Douglas ; Moonan, Patrick K. ; Munsiff, Sonal S. ; Kreiswirth, Barry N. ; Kurepina, Natalia ; Goranson, Christopher ; Ahuja, Shama D.
Description:

In 2004, identification of patients infected with the same Mycobacterium tuberculosis strain in New York, New York, USA, resulted in an outbreak investigation. The investigation involved data collection and analysis, establishing links between patients, and forming transmission hypotheses. Fifty-four geographically clustered cases were identified during 2003-2009. Initially, the M. tuberculosis strain was drug susceptible. However, in 2006, isoniazid resistance emerged, resulting in isoniazid-resistant M. tuberculosis among 17 (31%) patients. Compared with patients with drug-susceptible M. tuberculosis, a greater proportion of patients with isoniazid-resistant M. tuberculosis were US born and had a history of illegal drug use. No patients named one another as contacts. We used patient photographs to identify links between patients. Three links were associated with drug use among patients infected with isoniazid-resistant M. tuberculosis. The photographic method would have been more successful if used earlier in the investigation. Name-based contact investigation might not identify all contacts, particularly when illegal drug use is involved.
Subjects:

Adolescent Adult Aged Antitubercular Agents Child Cluster Analysis Disease Outbreaks Drug Resistance, Bacterial Drug Users Female Humans Isoniazid Male Microbial Sensitivity Tests Middle Aged Tuberculosis, Pulmonary Young Adult
Source:

Emerg Infect Dis. 17(3):372-378.
Document Type:

Journal Article
Place as Subject:

New York City, NY
Volume:

17
Issue:

3
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:e428952a1b14f1e638eb96de5b2a613d55d26c3dc1da60f2ca831425c4d73031
Download URL:

https://stacks.cdc.gov/view/cdc/18411/cdc_18411_DS1.pdf
File Type:

[PDF - 259.97 KB ]

File Language:

English

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