Influence of relative humidity on functional effects of an inhaled SO2-aerosol mixture.

Details

• Personal Author:
  Charlson RJ ; Frank R ; McJilton CE
• Description:
  Lightly anesthetized guinea pigs are exposed to 1 part per million of sulfur dioxide and 1 milligram per cubic meter of sodium chloride aerosol, individually and in combination, at low and high relative humidities. Changes in pulmonary mechanical function characterized by an increase in flow resistance and decrease in compliance are seen only when the mixture is administered at high relative humidity. The effect is ascribed to absorption of the highly soluble sulfur dioxide into the droplet before inhalation. [Description provided by NIOSH]
• Subjects:
  Air Pollutants, Occupational Hazardous Substances Occupational Health Particulate Matter Respiratory System Respiratory Tract Diseases Safety
• Keywords:
  Air-contaminants Inhalation NIOSH-Grant NIOSH-Publication Particulates Respiratory-system-disorders Toxic-gases
• ISSN:
  0003-0805
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 10 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  163-169
• Volume:
  113
• Issue:
  2
• NIOSHTIC Number:
  nn:00052075
• Citation:
  Am Rev Respir Dis 1976 Feb; 113(2):163-169
• Contact Point Address:
  Preventive Medicine University of Washington Dept of Preventive Medicine Seattle, Wash 98105
• CAS Registry Number:
  Sodium chloride (CAS RN 7647-14-5) ; Sulfur dioxide (CAS RN 7446-09-5)
• Federal Fiscal Year:
  1976
• NORA Priority Area:
  Pulmonary System Disorders
• Performing Organization:
  University of Washington, Seattle, Washington
• Peer Reviewed:
  True
• Start Date:
  19701001
• Source Full Name:
  American Review of Respiratory Disease
• End Date:
  19770331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:ee5c5f5dbd511db6c22072e56e636c9418eea908706d6616f0e18e822674a0c370f03c090fc84b378a1999e5e8a94e0004d873f5857d391c1e8769a0b6406fcf
• Download URL:
  https://stacks.cdc.gov/view/cdc/184066/cdc_184066_DS1.pdf
• File Type:
  [PDF - 574.85 KB ]