Effect of depth of inhalation on aerosol persistence during breath holding.

Details

• Personal Author:
  Altshuler B ; Goldring RM ; Palmes ED ; Wang C
• Description:
  Human subjects inhale aerosol bolus followed by 200-800 milliliters of clean air to a lung volume slightly below threshold limit concentration, to determine the effect of depth of inhalation on aerosol persistence in the respiratory tract during breath holding. The breath is then held from 0.5 to 20 seconds, after which a forced exhalation is made and aerosol recovery is measured as a function of inhaled volume and of time of breath. The bolus results are then compared with those for complete aerosol inhalations in which persistence is measured in the same way. Results show that depth of inhalation has a greater effect on persistence than would be predicted from some current lung models. [Description provided by NIOSH]
• Subjects:
  Lung Diseases Occupational Health Respiratory Tract Diseases Safety
• Keywords:
  Lung-disorders NIOSH-Grant NIOSH-Publication Physiological-measurements Pulmonary-system-disorders Respiratory-system-disorders
• ISSN:
  8750-7587
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  356-360
• Volume:
  34
• Issue:
  3
• NIOSHTIC Number:
  nn:00038651
• Citation:
  J Appl Physiol 1973 Mar; 34(3):356-360
• Contact Point Address:
  Environmental Medicine New York Univ Med Ctr 550 First Avenue New York, N Y 10016
• Federal Fiscal Year:
  1973
• NORA Priority Area:
  Pulmonary System Disorders
• Performing Organization:
  New York University, New York, New York
• Peer Reviewed:
  True
• Start Date:
  19681001
• Source Full Name:
  Journal of Applied Physiology
• End Date:
  19720430
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:50f97a6545e6c44a52559ce0d21d87c735ebb777ff36a73f9b717d186423b863adb47b55c19030f89f00026857c5091fe0db60cea71502d367a4b5c212dabbc9
• Download URL:
  https://stacks.cdc.gov/view/cdc/183993/cdc_183993_DS1.pdf
• File Type:
  [PDF - 1008.41 KB ]