Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus, Mexico

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Ramirez-Gonzalez, José Ernesto ; Gonzalez-Duran, Elizabeth ; Alcantara-Perez, Patricia ; Wong-Arambula, Claudia ; Olivera-Diaz, Hiram ; Cortez-Ortiz, Iliana ; Barrera-Badillo, Gisela ; Nguyen, Ha ; Gubareva, Larisa ; Lopez-Martinez, Irma ; Díaz-Quiñonez, Jose Alberto ; Lezana-Fernández, Miguel Angel ; Gatell-Ramírez, Hugo Lopez ; Villalobos, Jose Angel Cordova ; Hernández-Avila, Mauricio ; Alpuche-Aranda, Celia
• Description:
  During May 2009-April 2010, we analyzed 692 samples of pandemic (H1N1) 2009 virus from patients in Mexico. We detected the H275Y substitution of the neuraminidase gene in a specimen from an infant with pandemic (H1N1) 2009 who was treated with oseltamivir. This virus was susceptible to zanamivir and resistant to adamantanes and oseltamivir.
• Subjects:
  Adamantane Antiviral Agents Drug Resistance, Viral Female Humans Infant Influenza, Human Influenza A Virus, H1N1 Subtype Microbial Sensitivity Tests Neuraminidase Pandemics Point Mutation Reverse Transcriptase Polymerase Chain Reaction Zanamivir

  More +
• Source:
  Emerg Infect Dis. 17(2):283-286.
• Document Type:
  Journal Article
• Place as Subject:
  Mexico
• Volume:
  17
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:ea2d3a20525c9dd5808043f6085b5fb7caf2fa3d1b6ce8e785ec041291607c52
• Download URL:
  https://stacks.cdc.gov/view/cdc/18390/cdc_18390_DS1.pdf
• File Type:
  [PDF - 329.65 KB ]