Q Fever in France, 1985–2009

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Frankel, Diane ; Richet, Hervé ; Renvoisé, Aurélie ; Raoult, Didier
• Description:
  To assess Q fever in France, we analyzed data for 1985-2009 from the French National Reference Center. A total of 179,794 serum samples were analyzed; 3,723 patients (one third female patients) had acute Q fever. Yearly distribution of acute Q fever showed a continuous increase. Periodic variations were observed in monthly distribution during January 2000-December 2009; cases peaked during April-September. Q fever was diagnosed more often in patients in southeastern France, where our laboratory is situated, than in other areas. Reevaluation of the current positive predictive value of serologic analysis for endocarditis was performed. We propose a change in the phase I (virulent bacteria) immunoglobulin G cutoff titer to ≥1,600. Annual incidences of acute Q fever and endocarditis were 2.5/100,000 persons and 0.1/100,000 persons, respectively. Cases and outbreaks of Q fever have increased in France.
• Subjects:
  Adult Antibodies, Bacterial Bacteria Coxiella Burnetii Endocarditis Endocarditis, Bacterial Female France Geographic Repartition Humans Immunoglobulin G Incidence Male Middle Aged Outbreak Q Fever Seasonality Seasons Survey Synopsis

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• Source:
  Emerg Infect Dis. 17(3):350-356.
• Document Type:
  Journal Article
• Volume:
  17
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:13b680976bbe2d04f5d41ee90667a800fd0ad40aaf473b4b88007cdc422be9d9
• Download URL:
  https://stacks.cdc.gov/view/cdc/18384/cdc_18384_DS1.pdf
• File Type:
  [PDF - 280.06 KB ]