Content
and Copyright
i
Next-Generation Sequencing of Coccidioides immitis Isolated during Cluster Investigation
-
Published Date:
Feb 2011
Source:Emerg Infect Dis. 17(2):227-232.
[PDF-703.50 KB]
Details:
-
Alternative Title:Emerg Infect Dis
-
Personal Author:
-
Description:Next-generation sequencing enables use of whole-genome sequence typing (WGST) as a viable and discriminatory tool for genotyping and molecular epidemiologic analysis. We used WGST to confirm the linkage of a cluster of Coccidioides immitis isolates from 3 patients who received organ transplants from a single donor who later had positive test results for coccidioidomycosis. Isolates from the 3 patients were nearly genetically identical (a total of 3 single-nucleotide polymorphisms identified among them), thereby demonstrating direct descent of the 3 isolates from an original isolate. We used WGST to demonstrate the genotypic relatedness of C. immitis isolates that were also epidemiologically linked. Thus, WGST offers unique benefits to public health for investigation of clusters considered to be linked to a single source.
-
Subject:
-
Document Type:
-
Collection(s):
-
Main Document Checksum:
- File Type:
-
Supporting Files:
text/plain 
image/gif 
image/jpeg 
image/gif 
image/jpeg 
image/gif 
image/jpeg
text/plain
No Related Documents.
You May Also Like:
-
Published Date:Source:Description:File Type:[PDF - 599.41 KB]
File Type:[PDF - 599.41 KB]
Published Date:Source:Description:File Type:[PDF - 283.68 KB]
File Type:[PDF - 283.68 KB]
Published Date:Source:Description:File Type:[PDF - 841.77 KB]
File Type:[PDF - 841.77 KB]
Published Date:Source:Description:File Type:[PDF - 398.55 KB]
File Type:[PDF - 398.55 KB]
Published Date:Source:Description:File Type:[PDF - 594.54 KB]
File Type:[PDF - 594.54 KB]
Have Questions?
Visit CDC Info
Email
CDC-INFO
Open 24/7
CDC INFORMATION
CONNECT WITH CDC
