Prevalence of antibodies to environmental fungi in the sera of swine confinement.

Details

• Personal Author:
  Bledsoe, ToniA ; Donham K ; Lewis, Daniel M. ; Nicklow L ; Stasny A
• Description:
  As part of an epidemiological analysis of the respiratory hazards associated with working in swine-confinement facilities, we obtained serum samples from 292 persons who either work in swine-confinement facilities, farmers not engaged in swine production, or age-matched, non-farm workers. Environmental analyses of swine confinement facilities revealed six species of fungi were the predominant fungal isolates in these facilities. The sera were assayed for precipitating antibodies (IgG) by counterirnmuno-electrophoresis (CIEP) and reaginic antibodies (lgE) by a radioallergosorbent test (RAST) to extracts of the fungal isolates. The fungal isolates were Scopulariopsis sp., Penicillium sp., Cladosporium sp., Mucor sp., Aspergillus ochraceous., and Aspergillus flavum. Only two of the serum samples contained precipitating antibodies and both were reactive with the Mucor sp. isolate. In contrast, 46 of the 292 sera (15.7-) contained lgE antibodies to one or more of the fungal isolates. These results will be presented and discussed with respect to the exposure status of the workers, but the preliminary analysis indicates that lgE antibodies may be a more sensitive marker of exposure to these microorganisms than precipitating antibodies.
• Subjects:
  Accidents, Occupational Air Pollutants, Occupational Environmental Exposure Environmental Monitoring Manufacturing And Industrial Facilities Occupational Exposure Occupational Health Polystyrenes Safety Styrene
• Keywords:
  Agricultural-industry Agricultural-workers Animals Antibodies Blood Serum Confined Spaces Environmental Exposure Epidemiology Fungi Hazards Health-programs Humans Industrial-hazards Men Respiratory System Disorders Safety-practices Toxic-effects Women Worker-health

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• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Abstract
• Place as Subject:
  Iowa ; OSHA Region 3 ; OSHA Region 7 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  521
• NIOSHTIC Number:
  nn:20055971
• Citation:
  Papers and Proceedings of the Surgeon General's Conference on Agricultural Safety and Health (FarmSafe 2000). Myers ML, Herrick RF, Olenchock SA, Myers JR, Parker, John E., Hard DL, Wilson K, eds. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 92-105, 1992 Sep; :521
• Editor(s):
  Myers ML ; Herrick RF ; Olenchock SA ; Myers JR ; Parker, John E. ; Hard DL ; Wilson K
• Federal Fiscal Year:
  1992
• Peer Reviewed:
  False
• Source Full Name:
  Papers and Proceedings of the Surgeon General's Conference on Agricultural Safety and Health (FarmSafe 2000), April 30-May 3, 1991, Des Moines, Iowa
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:34d55bac749ca3e5c827953d44aa89abbc50cd5ea938632681bff1dccce1adeed8d95b9b4d3a386b98fad1f5cd6093eda8e1080ea72a8896a03c1413c4bd9205
• Download URL:
  https://stacks.cdc.gov/view/cdc/181748/cdc_181748_DS1.pdf
• File Type:
  [PDF - 57.71 KB ]