Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Wamala, Joseph F. ; Lukwago, Luswa ; Malimbo, Mugagga ; Nguku, Patrick ; Yoti, Zabulon ; ... More +
Wamala, Joseph F. ; Lukwago, Luswa ; Malimbo, Mugagga ; Nguku, Patrick ; Yoti, Zabulon ; Musenero, Monica ; Amone, Jackson ; Mbabazi, William ; Nanyunja, Miriam ; Zaramba, Sam ; Opio, Alex ; Lutwama, Julius J. ; Talisuna, Ambrose O. ; Okware, Sam I. Less -
Description:
During August 2007-February 2008, the novel Bundibugyo ebolavirus species was identified during an outbreak of Ebola viral hemorrhagic fever in Bundibugyo district, western Uganda. To characterize the outbreak as a requisite for determining response, we instituted a case-series investigation. We identified 192 suspected cases, of which 42 (22%) were laboratory positive for the novel species; 74 (38%) were probable, and 77 (40%) were negative. Laboratory confirmation lagged behind outbreak verification by 3 months. Bundibugyo ebolavirus was less fatal (case-fatality rate 34%) than Ebola viruses that had caused previous outbreaks in the region, and most transmission was associated with handling of dead persons without appropriate protection (adjusted odds ratio 3.83, 95% confidence interval 1.78-8.23). Our study highlights the need for maintaining a high index of suspicion for viral hemorrhagic fevers among healthcare workers, building local capacity for laboratory confirmation of viral hemorrhagic fevers, and institutionalizing standard precautions.
Subject:
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Adolescent
Adult
Aged
Child
Child, Preschool
Disease Outbreaks
Ebolavirus
Female
Hemorrhagic Fever, Ebola
Humans
Infant
Infant, Newborn
Male
Middle Aged
Risk Factors
Time Factors

Source:
Emerg Infect Dis. 16(7):1087-1092.
Document Type:
Journal Article
Place as Subject:
Uganda
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:463633e530d63e48b0f964393615a432a4bb7542178312dec3b679ae587cc086
File Type:

Supporting Files

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