Behavioral toxicity in silicotic patients (pilot study).

Details

• Personal Author:
  Chen F ; Song F ; Wu S ; Yuan G ; Zhang J
• Description:
  In order to explore the neuropsychological impairment in silica dust exposed workers, the Wechsler Adult Intelligence Scale Revised in China (WIAS-RC) was used along with some of the tests on the Wechsler Memory Scale Revised in China (WMS-RC) to examine eight men and one woman exposed to silica (14808607) dust. All had been exposed for at least 4 years and had been diagnosed as silicotic. Almost all of the subjects received full scores on experience and orientation subtests of WAIS-RC. Seven of nine cases got only a zero scaled score on the test of counting from 1 to 100. No one could completely recall a short story and no one could get more than a scaled score of seven on counting backward from 100. More than half failed to perform some subtests on WAIS-RC. The findings suggest that patients with silicosis suffered from some impairment of short term memory, but remote memory was spared. The poor performance on subtests of reversed counting and digits backward indicate that the mental tracking ability was markedly impaired. The patients did serial counting from 7 to 100 very slowly and most got only zero scaled score. The authors conclude that silica dust exposure caused chronic toxic effects on human behavior similar to those arising from organic solvent exposures.
• Subjects:
  Accidents, Occupational Hazardous Substances Lead Lead Poisoning Metals Metals, Heavy Metal Workers Nervous System Diseases Occupational Exposure Occupational Health Safety Urogenital Diseases Urogenital System

  More +
• Keywords:
  Dust Exposure Humans Nervous System Disorders Occupational Exposure Pneumoconiosis Psychological Effects Silica Dusts
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Conference/Symposia Proceedings
• Place as Subject:
  OSHA Region 3 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1573-1575
• NIOSHTIC Number:
  nn:00198619
• Citation:
  Proceedings of the VIIth International Pneumoconioses Conference, August 23-26, 1988, Pittsburgh, Pennsylvania, USA. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 90-108, 1990 Nov; (Part II):1573-1575
• CAS Registry Number:
  Quartz (SiO2) (CAS RN 14808-60-7)
• Federal Fiscal Year:
  1991
• Peer Reviewed:
  False
• Part Number:
  II
• Source Full Name:
  Proceedings of the VIIth International Pneumoconioses Conference, August 23-26, 1988, Pittsburgh, Pennsylvania, USA
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:50158c5b1e2f64df62f68cb632e10317d0bb1523cc59f668a1e12e4f9a37f3ecb93fa275cd72edb9d6a88948101dea1a8f10bc0e6d25b04059df6f309b26d161
• Download URL:
  https://stacks.cdc.gov/view/cdc/180562/cdc_180562_DS1.pdf
• File Type:
  [PDF - 82.73 KB ]