15 Year longitudinal studies of FEV1 loss and mucus hypersecretion development in coal workers in New South Wales, Australia.

Details

• Personal Author:
  Leigh J
• Description:
  Decreases in 1 second forced expiratory volume (FEV1) and development of mucus hypersecretion in Australian coal miners were examined. FEV1 data on 2807 males working in coal mines in New South Wales, Australia obtained during physical examinations between 30 June 1970 and 30 June 1973 were compared with data obtained between 30 June 1980 and 30 June 1983. The FEV1 data and data on age, height, cumulative current or previous dust exposure, current or previous tobacco use, and alcohol consumption were analyzed by logistic regression techniques. The mean decrease in FEV1 of the subjects over the study period was 0.81 liter. The FEV1 decrement was significantly, positively associated with age, previous dust exposure, previous smoking, and alcohol consumption. A second analysis was performed on 847 male coal miners who were examined at 5 year intervals between 30 June 1970 and 30 June 1985. Data on FEV1, smoking, alcohol use, the presence or absence of chronic mucus hypersecretion, and relative cumulative dust exposure were analyzed by logistic regression techniques. Chronic mucus hypersecretion and FEV1 per height squared (FEV1/h2) were used as dependent variables in the analyses. The extent of chronic mucus hypersecretion and airway obstruction, measured as FEV1/h2, increased over the study period. When controlled for age, chronic mucus hypersecretion was positively, significantly associated with relative dust exposure, smoking, and alcohol consumption. Airway obstruction was significantly positively associated with smoking and weakly associated with relative dust exposure and alcohol consumption. The authors conclude that a clear association between past dust exposure, smoking, and alcohol consumption and development of chronic mucus hypersecretion and airways obstruction has been demonstrated.
• Subjects:
  Accidents, Occupational Aerosols Atmosphere Chemistry Chemistry, Analytic Environmental Monitoring Humidity Laboratories Occupational Health Safety Solvents Temperature

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• Keywords:
  Airway Obstruction Body Fluids Cigarette Smoking Coal Dust Coal Miners Dust Exposure Epidemiology Occupational Health Pulmonary Function Tests Risk Factors
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Conference/Symposia Proceedings
• Place as Subject:
  OSHA Region 3 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  112-121
• NIOSHTIC Number:
  nn:00198416
• Citation:
  Proceedings of the VIIth International Pneumoconioses Conference, August 23-26, 1988, Pittsburgh, Pennsylvania, USA. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 90-108, 1990 Sep; (Part I):112-121
• Federal Fiscal Year:
  1990
• Peer Reviewed:
  False
• Part Number:
  I
• Source Full Name:
  Proceedings of the VIIth International Pneumoconioses Conference, August 23-26, 1988, Pittsburgh, Pennsylvania, USA
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:1a919b9a2a62d13cd1e7dc09d9523e36d9b8b3e0ac510bd2b76bca7c5655e8e02cddece85a4f4e6cc11358f09bd58b278b83754570e638c79934e74102bfa9e5
• Download URL:
  https://stacks.cdc.gov/view/cdc/180479/cdc_180479_DS1.pdf
• File Type:
  [PDF - 201.20 KB ]