Epidemiology of asbestos related diseases.

Details

• Personal Author:
  Dement, John M.
• Description:
  Although there were several anecdotal reports from earlier times, the first well documented case of asbestosis was reported in 1906 in a worker engaged in the production of asbestos (1332214) textiles. In 1917 a report of ten cases of pulmonary fibrosis occurring at a Pennsylvania facility was published. The first detailed epidemiologic study of asbestos workers was undertaken in Great Britain in 1928. The first indication that asbestos might be a human carcinogen came in 1935 with the report of three independently diagnosed cases of lung cancer detected during autopsy of asbestos workers. Epidemiologic studies have now repeatedly demonstrated an association between asbestos exposure and increased mortality due to asbestosis, lung cancer, pleural and peritoneal mesothelioma, and gastrointestinal cancer. In some studies asbestos exposure has also been associated with increased risks for laryngeal cancer and cancer of the buccal cavity and pharynx. Studies which have been concerned with exposure to crocidolite (12001284), amosite (12172735), anthophyllite (17068789), tremolite (14567738), and chrysotile (12001295 ) were highlighted. Other topics reviewed included asbestos contamination of other minerals, the combined effects of asbestos exposure and tobacco smoke, mortality and pleural radiographic changes, and mixed fiber exposures.
• Subjects:
  Accidents, Occupational Air Pollutants, Occupational Air Pollution, Indoor Environmental Exposure Environmental Health Environmental Monitoring Environmental Pollution Epidemiology Nitrogen Oxides Occupational Health Safety Sulfur Compounds

  More +
• Keywords:
  Asbestos-dust Asbestos-fibers Asbestos-products Asbestos-workers Mortality-rates NIOSH-Author Pulmonary-system-disorders Risk-analysis Textiles-industry
• Document Type:
  Text
• Genre:
  Other
• Place as Subject:
  OSHA Region 3 ; Pennsylvania ; Virginia ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-46
• NIOSHTIC Number:
  nn:00192306
• Citation:
  NIOSH 1981 Jul; :1-46
• CAS Registry Number:
  Asbestos (CAS RN 1332-21-4) ; Crocidolite asbestos (CAS RN 12001-28-4) ; Amosite asbestos (CAS RN 12172-73-5) ; Anthophyllite (CAS RN 17068-78-9) ; Tremolite (Ca2[(Mg0.9-1Fe0-0.1)4.5-5Al0-0.5](Si7.5-8Al0-0.5)(OH)2O22) (CAS RN 14567-73-8)
• Federal Fiscal Year:
  1981
• NORA Priority Area:
  Asthma and Chronic Obstructive Pulmonary Disease ; Disease and Injury ; Pulmonary System Disorders
• Peer Reviewed:
  False
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:ad295a2c08b080b00bcfd67b7cbc01b6c5aea7b96c747740a0f032d156c9d08679f5a76586782f87b7c17413c9eede56d5a5078c1ccf767ac89cac431915c722
• Download URL:
  https://stacks.cdc.gov/view/cdc/180299/cdc_180299_DS1.pdf
• File Type:
  [PDF - 1.59 MB ]