Decreasing Shigellosis-related Deaths without Shigella spp.–specific Interventions, Asia
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Decreasing Shigellosis-related Deaths without Shigella spp.–specific Interventions, Asia

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  • Details:

    • Alternative Title:
      Emerg Infect Dis
    • Description:
      In 1999, a review of the literature for 1966-1997 suggested that ≈1.1 million persons die annually of shigellosis, including ≈880,000 in Asia. Our recent review of the literature for 1990-2009 indicates that ≈125 million shigellosis cases occur annually in Asia, of which ≈14,000 are fatal. This estimate for illnesses is similar to the earlier estimate, but the number of deaths is 98% lower; that is, the lower estimate of deaths is associated with markedly reduced case-fatality rates rather than fewer cases. Shigella spp.-related deaths decreased substantially during a period without Shigella spp.-specific interventions. We speculate that nonspecific interventions, e.g., measles vaccination, vitamin A supplementation, and improved nutrition, may have led to the reduced number of shigellosis-related deaths.
    • Source:
      Emerg Infect Dis. 16(11):1718-1723.
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