Carcinogenic potential of condensed pyrolysis effluents from iron foundry casting operations, volume IV.

Details

• Personal Author:
  Garner FM ; Plankenhorn LJ ; Shellenberger TE
• Description:
  Data tabulations for a carcinogenic bioassay of condensed effluents from iron foundry casting operations that used hamsters as the test species are presented. In that study, Syrian-golden-hamsters were administered effluents from shell sand, green sand, furan (110009), or urethane (51796) casting molds by intratracheal instillation once a week for 18 weeks. The concentrations were 5 or 10 milligrams (mg) effluent in 0.2 milliliter distilled water, except for effluents from the urethane mold which were administered in amounts of 2.5 or 5.0mg. The animals were maintained until 98 percent mortality occurred or until week 103 or 117. None of the effluents were found to be carcinogenic at the concentrations used. An individual mortality inventory for each animal was calculated. Data for a survival analysis using the Kaplan Meier product limit method was tabulated. Data tables of individual and mean body weights of males for weeks 1 through 111 and females for weeks 11 through 102 were prepared. Data for the statistical analysis of body weight changes of males and females were also tabulated.
• Subjects:
  Accidents, Occupational Occupational Health Preceptorship Safety Textile Industry
• Keywords:
  Contract-210-78-0033 Data-processing Equipment-design Iron-oxide-fumes Iron-working-industry Lung-fibrosis NIOSH-Contract Pharmacodynamics Pyrolysis Quantitative-analysis Toxicology

  More +
• Document Type:
  Text
• Funding:
  Contract
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DBBS - Division of Biomedical and Behavioral Sciences
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-185
• NIOSHTIC Number:
  nn:00144930
• Citation:
  NIOSH 1984 Oct; :1-185
• CAS Registry Number:
  Furan (CAS RN 110-00-9) ; Carbamic acid, ethyl ester (CAS RN 51-79-6)
• Federal Fiscal Year:
  1985
• Peer Reviewed:
  False
• Source Full Name:
  Experimental Toxicology Branch, Division of Biomedical and Behavioral Science, NIOSH, U.S. Department of Health and Human Services, Cincinnati, Ohio
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:077d4a8efb205cc7aeea9e2879ad8d200d08530d3f31f7cbc5bcb369651939bfd75017ba4e67d61fc7a0d2db7626d39db2ddbd1284c434b3bd49c182805eb400
• Download URL:
  https://stacks.cdc.gov/view/cdc/179696/cdc_179696_DS1.pdf
• File Type:
  [PDF - 8.34 MB ]