Serologic Markers for Detecting Malaria in Areas of Low Endemicity, Somalia, 2008

Bousema, Teun; Youssef, Randa M.; Cook, Jackie; Cox, Jonathan; Alegana, Victor A.; Amran, Jamal; Noor, Abdisalan M.; Snow, Robert W.; Drakeley, Chris

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Serologic Markers for Detecting Malaria in Areas of Low Endemicity, Somalia, 2008

Published Date:

Mar 2010

Source:

Emerg Infect Dis. 16(3):392-399.

[PDF - 259.96 KB]

Details:

Personal Authors:

Bousema, Teun ; Youssef, Randa M. ; Cook, Jackie ; Cox, Jonathan ; Alegana, Victor A. ; ... More ▼

Keywords:

[+]

Description:

Areas in which malaria is not highly endemic are suitable for malaria elimination, but assessing transmission is difficult because of lack of sensitivity of commonly used methods. We evaluated serologic markers for detecting variation in malaria exposure in Somalia. Plasmodium falciparum or P. vivax was not detected by microscopy in cross-sectional surveys of samples from persons during the dry (0/1,178) and wet (0/1,128) seasons. Antibody responses against P. falciparum or P. vivax were detected in 17.9% (179/1,001) and 19.3% (202/1,044) of persons tested. Reactivity against P. falciparum was significantly different between 3 villages (p<0.001); clusters of seroreactivity were present. Distance to the nearest seasonal river was negatively associated with P. falciparum (p = 0.028) and P. vivax seroreactivity (p = 0.016). Serologic markers are a promising tool for detecting spatial variation in malaria exposure and evaluating malaria control efforts in areas where transmission has decreased to levels below the detection limit of microscopy.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

09-0732-F1.gif	image/gif
09-0732-F1.jpg	image/jpeg
09-0732-F2.gif	image/gif
09-0732-F2.jpg	image/jpeg
09-0732_finalR.nxml	text/plain
license.txt	text/plain

No Related Documents.

You May Also Like:

Malaria surveillance in low-transmission areas of Zambia using reactive case detection

Personal Author:

Larsen, David A.; Chisha, Zunda; Winters, Benjamin; Mwanza, Mercie; Kamuliwo, Mulakwa; Mbwili, Clara; Hawela, Moonga; Hamainza, Busiku; Chirwa, Jacob; Craig, Allen S.; Rutagwera, Marie-Reine; Lungu, Chris; Ngwenya-Kangombe, Tokozile; Cheelo, Sanford; Miller, John M.; Bridges, Daniel J.; Winters, Anna M.;

Published:

Nov 19 2015

Source:

Malar J. 14.

Description:

Background : Repeat national household surveys suggest highly variable malaria transmission and increasing coverage of high-impact malaria interventions throughout Zambia. Many areas of very low malaria transmission, especially across southern and ce...

File Type:

[PDF - 3.06 MB]
Mass ivermectin treatment for Onchocerciasis: Lack of evidence for collateral impact on transmission of Wuchereria bancrofti in areas of co-endemicity

Personal Author:

Richards, FO; Eigege, A; Pam, D; Kal, A; Lenhart, A; Oneyka, JOA; Jinadu, MY; Miri, ES;

Published:

Jul 15 2005

Source:

Filaria J. 2005; 4:6.

Description:

There has long been interest in determining if mass ivermectin administration for onchocerciasis has 'unknowingly' interrupted lymphatic filariasis (LF) transmission where the endemicity of the two diseases' overlaps. We studied 11 communities in cen...

File Type:

[PDF - 198.99 KB]
Evaluation of a laboratory quality assurance pilot programme for malaria diagnostics in low-transmission areas of Kenya, 2013

Personal Author:

Wanja, Elizabeth; Achilla, Rachel; Obare, Peter; Adeny, Rose; Moseti, Caroline; Otieno, Victor; Morang’a, Collins; Murigi, Ephantus; Nyamuni, John; Monthei, Derek R.; Ogutu, Bernhards; Buff, Ann M.;

Published:

May 25 2017

Source:

Malar J. 16.

Description:

Background : One objective of the Kenya National Malaria Strategy 2009–2017 is scaling access to prompt diagnosis and effective treatment. In 2013, a quality assurance (QA) pilot was implemented to improve accuracy of malaria diagnostics at selecte...

File Type:

[PDF - 1.23 MB]
Artemisinin combination therapy mass drug administration in a setting of low malaria endemicity: programmatic coverage and adherence during an observational study in Zanzibar

Personal Author:

Ali, Abdullah S.; Thawer, Narjis G.; Khatib, Bakar; Amier, Haji H.; Shija, Joseph; Msellem, Mwinyi; Al-mafazy, Abdul-wahid; Garimo, Issa A.; Mkali, Humphrey; Ramsan, Mahdi M.; Kafuko, Jessica M.; Paxton, Lynn A.; Reithinger, Richard; Ngondi, Jeremiah M.;

Published:

Aug 14 2017

Source:

Malar J. 16.

Description:

Background : Mass drug administration (MDA) appears to be effective in reducing the risk of malaria parasitaemia. This study reports on programmatic coverage and compliance of MDA using artemisinin-based combination therapy (ACT) in four shehias (sma...

File Type:

[PDF - 1.01 MB]
Identification of Serologic Markers for School-Aged Children With Congenital Rubella Syndrome

Personal Author:

Hyde, Terri B.; Sato, Helena Keico; Hao, LiJuan; Flannery, Brendan; Zheng, Qi; Wannemuehler, Kathleen; Ciccone, Flávia Helena; de Sousa Marques, Heloisa; Weckx, Lily Yin; Sáfadi, Marco Aurélio; de Oliveira Moraes, Eliane; Pinhata, Marisa Mussi; Neto, Jaime Olbrich; Bevilacqua, Maria Cecilia; Junior, Alfredo Tabith; Monteiro, Tatiana Alves; Figueiredo, Cristina Adelaide; Andrus, Jon K.; Reef, Susan E.; Toscano, Cristiana M.; Castillo-Solorzano, Carlos; Icenogle, Joseph P.;

Published:

Oct 31 2014

Source:

J Infect Dis. 212(1):57-66.

Description:

Background : Congenital rubella syndrome (CRS) case identification is challenging in older children since laboratory markers of congenital rubella virus (RUBV) infection do not persist beyond age 12 months. : Methods : We enrolled children with CRS b...

File Type:

[PDF - 522.40 KB]