Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Bousema, Teun ; Youssef, Randa M. ; Cook, Jackie ; Cox, Jonathan ; Alegana, Victor A. ; ... More +
Bousema, Teun ; Youssef, Randa M. ; Cook, Jackie ; Cox, Jonathan ; Alegana, Victor A. ; Amran, Jamal ; Noor, Abdisalan M. ; Snow, Robert W. ; Drakeley, Chris Less -
Description:
Areas in which malaria is not highly endemic are suitable for malaria elimination, but assessing transmission is difficult because of lack of sensitivity of commonly used methods. We evaluated serologic markers for detecting variation in malaria exposure in Somalia. Plasmodium falciparum or P. vivax was not detected by microscopy in cross-sectional surveys of samples from persons during the dry (0/1,178) and wet (0/1,128) seasons. Antibody responses against P. falciparum or P. vivax were detected in 17.9% (179/1,001) and 19.3% (202/1,044) of persons tested. Reactivity against P. falciparum was significantly different between 3 villages (p<0.001); clusters of seroreactivity were present. Distance to the nearest seasonal river was negatively associated with P. falciparum (p = 0.028) and P. vivax seroreactivity (p = 0.016). Serologic markers are a promising tool for detecting spatial variation in malaria exposure and evaluating malaria control efforts in areas where transmission has decreased to levels below the detection limit of microscopy.
Subjects:
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Adolescent Animals Anopheles Antibodies, Protozoan Child Child, Preschool Cross-Sectional Studies Humans Malaria, Falciparum Malaria, Vivax Prevalence Seasons
Source:
Emerg Infect Dis. 16(3):392-399.
Document Type:
Journal Article
Place as Subject:
Somalia
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:9a0f8dbfb77db2f14cf0448bb80584453dfdf1ccb17121d943a8e163a0f6ff9c
Download URL:
https://stacks.cdc.gov/view/cdc/17960/cdc_17960_DS1.pdf
File Type:

Supporting Files

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