DOP substitutes for quantitative fit testing: aerosol.

Details

• Personal Author:
  Baron, PaulA ; Doemeny LJ ; Kennedy E ; Reed, Laurence D. ; Smith JP ; Sterling DC
• Description:
  Substitutes for the test agent diethyl(hexyl)phthalate (117817) (DOP) used in respirator quantitative fit testing were investigated. Recent medical evidence has implicated DOP in the causation of liver cancer in test animals. Several model fluids with physical properties similar to those of DOP were examined. They were: diethyl(hexyl)sebacate (122623), linoleic-acid (60333), oleic-acid (112801), dimethicone (9006659), and corn-oil. The fit test apparatus generated aerosols from these fluids and chemical properties were observed. The fit test apparatus was capable of producing the required quantities of aerosol from all the fluids tested. Mass median diameters and geometric standard deviations of the aerosols were all comparable. The required protection factor could be measured with the aerosols produced from any of the oils tested. The authors note that oils with physical properties similar to those of DOP are potential candidate materials for use in quantitative fit testing.
• Subjects:
  Accidents, Occupational Biological Assay Cytology Genetics Laboratories Occupational Exposure Occupational Health Safety Workplace
• Keywords:
  Aerosol-generators Chemical-properties Human-factors-engineering Materials-testing Quantitative-analysis Respiratory-protective-equipment Safety-engineering
• Document Type:
  Text
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DPSE - Division of Physical Sciences and Engineering
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-15
• NIOSHTIC Number:
  nn:00124133
• Citation:
  NIOSH 1980 Sep; :1-15
• CAS Registry Number:
  Dioctyl phthalate (CAS RN 117-81-7) ; Bis(2-ethylhexyl) sebacate (CAS RN 122-62-3) ; Linoleic acid (CAS RN 60-33-3) ; Oleic acid (CAS RN 112-80-1) ; Dimethicone (CAS RN 9006-65-9)
• Federal Fiscal Year:
  1980
• Peer Reviewed:
  False
• Source Full Name:
  Division of Physical Sciences and Engineering, NIOSH, Cincinnati, Ohio, 15 pages, 15 references
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:13a9d5128dd557df28bac5349e4273551cef9ecd64c5eb7e1f785de7c843282e0479a4b64f458aaec427eaf758a849316d7e00bc35752783d5f7b073ddb9679a
• Download URL:
  https://stacks.cdc.gov/view/cdc/179498/cdc_179498_DS1.pdf
• File Type:
  [PDF - 559.04 KB ]