Industrial hygiene study of workers exposed to nitrosamines.

Details

• Personal Author:
  Fajen JM
• Description:
  Occupational exposure to nitrosamines was studied. Air samples were collected in 37 different manufacturing facilities including the azo dye industry, fish processing industry, fish meal manufacturing, cutting fluid manufacturers and users, and rubber and tanning industries. Nitrosamines in air were analyzed by gas chromatography and high pressure liquid chromatography using the Thermal Energy Analyzer (TEA) as a detector. All industries except fish processing had airborne concentrations of TEA responsive compounds. Concentrations of TEA responsive material were as high as 40 micrograms per cubic meter (micrograms/CuM) in the dye industry. A factory using cutting fluids had air concentrations of 0.08 nanograms per cubic meter of N-nitrosodiethanolamine (1116547). A fish meal factory had air concentrations of 0.06micrograms/CuM N- nitrosodimethylamine (62759) (NDMA). Air concentrations of NDMA in a chrome tannery were 47micrograms/CuM. N-nitrosomorpholine (59892) (NMOR) concentrations in the rubber industry were as high as 250micrograms/CuM. Air samples from a rubber chemical manufacturing facility contained NDMA and N-nitrosodiphenylamine (86306) as well as NMOR. The authors conclude that nitrosamine exposure in a variety of industries may be as large as that in the tire and rubber industry.
• Subjects:
  Accidents, Occupational Aerospace Medicine Aircraft Delivery Of Health Care Emergencies Emergency Responders Occupational Health Safety
• Keywords:
  Air-contamination Air-sampling Carcinogens Dyes Health-surveys Industrial-hygiene Nitro-compounds
• Publisher:
  NCI; EPA; NIOSH
• Document Type:
  Text
• Genre:
  Conference/Symposia Proceedings
• Place as Subject:
  District of Columbia ; Maryland ; OSHA Region 3
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  121-138
• NIOSHTIC Number:
  nn:00123099
• Citation:
  Proceedings of the first NCI/EPA/NIOSH collaborative workshop: progress on joint environmental and occupational cancer studies, May 6-8, 1980, Rockville, Maryland. Kraybill HF, Blackwood IC, Freas NB, eds. Washington, DC: National Cancer Institute, Environmental Protection Agency, National Institute for Occupational Safety and Health, 1980 May; :121-138
• CAS Registry Number:
  N-Nitrosodiethanolamine (CAS RN 1116-54-7) ; N-Nitrosodimethylamine (CAS RN 62-75-9) ; Nitrosomorpholine (CAS RN 59-89-2) ; N-Nitrosodiphenylamine (CAS RN 86-30-6)
• Editor(s):
  Kraybill HF ; Blackwood IC ; Freas NB
• Federal Fiscal Year:
  1980
• Peer Reviewed:
  False
• Source Full Name:
  Proceedings of the first NCI/EPA/NIOSH collaborative workshop: progress on joint environmental and occupational cancer studies, May 6-8, 1980, Rockville, Maryland
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:fa96c4f8cd6eec446026313ab67bafecf99efcf1829153fc28b8af6f444e7d473a415e80f9ee181d95f48df4178b5ee8b755af0df18ab2413fefbb790fce637a
• Download URL:
  https://stacks.cdc.gov/view/cdc/179474/cdc_179474_DS1.pdf
• File Type:
  [PDF - 603.64 KB ]