Fine-scale Identification of the Most Likely Source of a Human Plague Infection

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Colman, Rebecca E. ; Vogler, Amy J. ; Lowell, Jennifer L. ; Gage, Kenneth L. ; Morway, Christina ; Reynolds, Pamela J. ; Ettestad, Paul ; Keim, Paul ; Kosoy, Michael Y. ; Wagner, David M.
• Description:
  We describe an analytic approach to provide fine-scale discrimination among multiple infection source hypotheses. This approach uses mutation-rate data for rapidly evolving multiple locus variable-number tandem repeat loci in probabilistic models to identify the most likely source. We illustrate the utility of this approach using data from a North American human plague investigation.
• Subjects:
  • Evolution, Molecular
  • Genotype
  • Humans
  • Models, Statistical
  • Molecular Epidemiology
  • Mutation
  • Plague
• Source:
  Emerg Infect Dis. 15(10):1623-1625.
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  New Mexico
• Volume:
  15
• Issue:
  10
• Download URL:
  https://stacks.cdc.gov/view/cdc/17842/cdc_17842_DS1.pdf
• File Type:
  [PDF - 474.26 KB]
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha-512:3885194a0ff1c01b68451ad07269d99a8e0a494057305dac094576ed258d5a8abe6bfcd4795c722c62ea21f028768f7a24d4978522019602d16b81bee269dd50