Fine-scale Identification of the Most Likely Source of a Human Plague Infection

Colman, Rebecca E.; Vogler, Amy J.; Lowell, Jennifer L.; Gage, Kenneth L.; Morway, Christina; Reynolds, Pamela J.; Ettestad, Paul; Keim, Paul; Kosoy, Michael Y.; Wagner, David M.

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Fine-scale Identification of the Most Likely Source of a Human Plague Infection

Oct 2009
By Colman, Rebecca E. ; Vogler, Amy J. ; Lowell, Jennifer L. ; ...
Source: Emerg Infect Dis. 15(10):1623-1625.

[PDF-474.26 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Colman, Rebecca E. ; Vogler, Amy J. ; Lowell, Jennifer L. ; Gage, Kenneth L. ; Morway, Christina ; ... More +

Colman, Rebecca E. ; Vogler, Amy J. ; Lowell, Jennifer L. ; Gage, Kenneth L. ; Morway, Christina ; Reynolds, Pamela J. ; Ettestad, Paul ; Keim, Paul ; Kosoy, Michael Y. ; Wagner, David M. Less -
Description:

We describe an analytic approach to provide fine-scale discrimination among multiple infection source hypotheses. This approach uses mutation-rate data for rapidly evolving multiple locus variable-number tandem repeat loci in probabilistic models to identify the most likely source. We illustrate the utility of this approach using data from a North American human plague investigation.
Subjects:

[+]

Evolution, Molecular Genotype Humans Models, Statistical Molecular Epidemiology Mutation Plague
Source:

Emerg Infect Dis. 15(10):1623-1625.
Document Type:

Journal Article
Place as Subject:

New Mexico
Volume:

15
Issue:

10
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:055122c58f2418f560bd1b3ab69ec958f038abec12a9c7c7116b4088b294a634
Download URL:

https://stacks.cdc.gov/view/cdc/17842/cdc_17842_DS1.pdf
File Type:

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