Fine-scale Identification of the Most Likely Source of a Human Plague Infection

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Colman, Rebecca E. ; Vogler, Amy J. ; Lowell, Jennifer L. ; Gage, Kenneth L. ; Morway, Christina ; Reynolds, Pamela J. ; Ettestad, Paul ; Keim, Paul ; Kosoy, Michael Y. ; Wagner, David M.
• Description:
  We describe an analytic approach to provide fine-scale discrimination among multiple infection source hypotheses. This approach uses mutation-rate data for rapidly evolving multiple locus variable-number tandem repeat loci in probabilistic models to identify the most likely source. We illustrate the utility of this approach using data from a North American human plague investigation.
• Subjects:
  Evolution, Molecular Genotype Humans Models, Statistical Molecular Epidemiology Mutation Plague
• Source:
  Emerg Infect Dis. 15(10):1623-1625.
• Document Type:
  Journal Article
• Place as Subject:
  New Mexico
• Volume:
  15
• Issue:
  10
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:055122c58f2418f560bd1b3ab69ec958f038abec12a9c7c7116b4088b294a634
• Download URL:
  https://stacks.cdc.gov/view/cdc/17842/cdc_17842_DS1.pdf
• File Type:
  [PDF - 474.26 KB ]