Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Ayelet, Gelagay ; Mahapatra, Mana ; Gelaye, Esayas ; Egziabher, Berhe G. ; Rufeal, Tesfaye ; ... More +
Ayelet, Gelagay ; Mahapatra, Mana ; Gelaye, Esayas ; Egziabher, Berhe G. ; Rufeal, Tesfaye ; Sahle, Mesfin ; Ferris, Nigel P. ; Wadsworth, Jemma ; Hutchings, Geoffrey H. ; Knowles, Nick J. Less -
Description:
Foot-and-mouth disease (FMD) is endemic to sub-Saharan Africa. To further understand its complex epidemiology, which involves multiple virus serotypes and host species, we characterized the viruses recovered from FMD outbreaks in Ethiopia during 1981-2007. We detected 5 of the 7 FMDV serotypes (O, A, C, Southern African Territories [SAT] 1, and SAT 2). Serotype O predominated, followed by serotype A; type C was not recognized after 1983. Phylogenetic analysis of virus protein 1 sequences indicated emergence of a new topotype within serotype O, East Africa 4. In 2007, serotype SAT 1 was detected in Ethiopia and formed a new distinct topotype (IX), and serotype SAT 2 reappeared after an apparent gap of 16 years. The diversity of viruses highlights the role of this region as a reservoir for FMD virus, and their continuing emergence in Ethiopia will greatly affect spread and consequent control strategy of the disease on this continent.
Subject:
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Animals
Cattle
Cattle Diseases
Cell Line
Cricetinae
Disease Outbreaks
Foot-and-Mouth Disease
Foot-and-Mouth Disease Virus
Genetic Variation
Goat Diseases
Goats
Molecular Sequence Data
Phylogeny
Research
Sequence Analysis, DNA
Serotyping
Sheep
Sheep Diseases

Source:
Emerg Infect Dis. 15(9):1409-1417.
Document Type:
Journal Article
Place as Subject:
Ethiopia
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:0b4ec2a0d165c25ea5fa32e4d2e9d2337cd3bf8f4d0bddc77bacab6b3e307a8b
File Type:

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