Characterization of Avian Influenza Viruses A (H5N1) from Wild Birds, Hong Kong, 2004–2008

Smith, Gavin J.D.; Vijaykrishna, Dhanasekaran; Ellis, Trevor M.; Dyrting, Kitman C.; Leung, Y.H. Connie; Bahl, Justin; Wong, Chun W.; Kai, Huang; Chow, Mary K.W.; Duan, Lian; Chan, Allen S.L.; Zhang, Li Juan; Chen, Honglin; Luk, Geraldine S.M.; Peiris, J.S. Malik; Guan, Yi

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Characterization of Avian Influenza Viruses A (H5N1) from Wild Birds, Hong Kong, 2004–2008

Supporting Files Public Domain

Mar 2009
By Smith, Gavin J.D. ; Vijaykrishna, Dhanasekaran ; Ellis, Trevor M. ; ...

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Smith, Gavin J.D. ; Vijaykrishna, Dhanasekaran ; Ellis, Trevor M. ; Dyrting, Kitman C. ; Leung, Y.H. Connie ; Bahl, Justin ; Wong, Chun W. ; Kai, Huang ; Chow, Mary K.W. ; Duan, Lian ; Chan, Allen S.L. ; Zhang, Li Juan ; Chen, Honglin ; Luk, Geraldine S.M. ; Peiris, J.S. Malik ; Guan, Yi
Description:

From January 2004 through June 2008, surveillance of dead wild birds in Hong Kong, People's Republic of China, periodically detected highly pathogenic avian influenza (HPAI) viruses (H5N1) in individual birds from different species. During this period, no viruses of subtype H5N1 were detected in poultry on farms and in markets in Hong Kong despite intensive surveillance. Thus, these findings in wild birds demonstrate the potential for wild birds to disseminate HPAI viruses (H5N1) to areas otherwise free from the viruses. Genetic and antigenic characterization of 47 HPAI (H5N1) viruses isolated from dead wild birds in Hong Kong showed that these isolates belonged to 2 antigenically distinct virus groups: clades 2.3.4 and 2.3.2. Although research has shown that clade 2.3.4 viruses are established in poultry in Asia, the emergence of clade 2.3.2 viruses in nonpasserine birds from Hong Kong, Japan, and Russia raises the possibility that this virus lineage may have become established in wild birds.
Subjects:

Animals Animals, Wild Bird Diseases Birds Hemagglutination Inhibition Tests Highly Pathogenic Avian Influenza Hong Kong Influenza A Virus, H5N1 Subtype Influenza In Birds Molecular Epidemiology Molecular Sequence Data Phylogeny Polymerase Chain Reaction Research Sequence Analysis, DNA Virus Evolution
Source:

Emerg Infect Dis. 15(3):402-407.
Document Type:

Journal Article
Volume:

15
Issue:

3
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:26f902622570f8a1552ab1a0a0ef2f6a71a9c6051d224718697e4fb4a55ce486
Download URL:

https://stacks.cdc.gov/view/cdc/17731/cdc_17731_DS1.pdf
File Type:

[PDF - 200.79 KB ]

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