Severe Dengue Epidemics in Sri Lanka, 2003–2006

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Kanakaratne, Nalaka ; Wahala, Wahala M.P.B. ; Messer, William B. ; Tissera, Hasitha A. ; Shahani, Aruna ; Abeysinghe, Nihal ; de Silva, Aravinda M. ; Gunasekera, Maya
• Description:
  Recent emergence of dengue hemorrhagic fever in the Indian subcontinent has been well documented in Sri Lanka. We compare recent (2003-2006) and past (1980-1997) dengue surveillance data for Sri Lanka. The 4 dengue virus (DENV) serotypes have been cocirculating in Sri Lanka for >30 years. Over this period, a new genotype of DENV-1 has replaced an old genotype. Moreover, new clades of DENV-3 genotype III viruses have replaced older clades. Emergence of new clades of DENV-3 in 1989 and 2000 coincided with abrupt increases in the number of reported dengue cases, implicating this serotype in severe epidemics. In 1980-1997, most reported dengue cases were in children. Recent epidemics have been characterized by many cases in children and adults. Changes in local transmission dynamics and genetic changes in DENV-3 are likely increasing emergence of severe dengue epidemics in Sri Lanka.
• Subjects:
  Adolescent Adult Age Distribution Animals Child Child, Preschool Communicable Diseases, Emerging Dengue Virus Disease Outbreaks Genotype Humans Infant Infant, Newborn Middle Aged Phylogeny Research Sequence Analysis, DNA Serotyping Severe Dengue Severity Of Illness Index Young Adult

  More +
• Source:
  Emerg Infect Dis. 15(2):192-199.
• Document Type:
  Journal Article
• Place as Subject:
  Sri Lanka
• Location:
  Asia
• Volume:
  15
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:b3039723dd69ce0649b176a229de86fbeb3b6f6dc387ab9a804e035bc74c40b9
• Download URL:
  https://stacks.cdc.gov/view/cdc/17386/cdc_17386_DS1.pdf
• File Type:
  [PDF - 439.91 KB ]