Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Manges, Amee R. ; Tabor, Helen ; Tellis, Patricia ; Vincent, Caroline ; Tellier, Pierre-Paul
Manges, Amee R. ; Tabor, Helen ; Tellis, Patricia ; Vincent, Caroline ; Tellier, Pierre-Paul Less -
Description:
Women with urinary tract infections (UTIs) in California, USA (1999-2001), were infected with closely related or indistinguishable strains of Escherichia coli (clonal groups), which suggests point source dissemination. We compared strains of UTI-causing E. coli in California with strains causing such infections in Montréal, Québec, Canada. Urine specimens from women with community-acquired UTIs in Montréal (2006) were cultured for E. coli. Isolates that caused 256 consecutive episodes of UTI were characterized by antimicrobial drug susceptibility profile, enterobacterial repetitive intergenic consensus 2 PCR, serotyping, XbaI and NotI pulsed-field gel electrophoresis, multilocus sequence typing, and phylogenetic typing. We confirmed the presence of drug-resistant, genetically related, and temporally clustered E. coli clonal groups that caused community-acquired UTIs in unrelated women in 2 locations and 2 different times. Two clonal groups were identified in both locations. Epidemic transmission followed by endemic transmission of UTI-causing clonal groups may explain these clusters of UTI cases.
Subjects:
[+]
Adolescent Adult Antimicrobial Drug Resistance Bacterial Typing Techniques California Cluster Analysis Community-Acquired Infections Cross-Sectional Studies Disease Outbreaks DNA Fingerprinting Drug Resistance, Multiple, Bacterial Escherichia Coli Escherichia Coli Infections Extraintestinal Infections Female Humans Middle Aged Molecular Epidemiology Phylogeny Quebec Research Serotyping Urinary Tract Infections
Source:
Emerg Infect Dis. 14(10):1575-1583
Pubmed ID:
18826822
Pubmed Central ID:
PMC2609861
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:5e2bf702130bb36712b9371295a2d56928bb92b152a61631f0f099da171bf1d9
Download URL:
https://stacks.cdc.gov/view/cdc/17199/cdc_17199_DS1.pdf
File Type:

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