High Genetic Diversity of Measles Virus, World Health Organization European Region, 2005–2006

Kremer, Jacques R.; Brown, Kevin E.; Jin, Li; Santibanez, Sabine; Shulga, Sergey V.; Aboudy, Yair; Demchyshyna, Irina V.; Djemileva, Sultana; Echevarria, Juan E.; Featherstone, David F.; Hukic, Mirsada; Johansen, Kari; Litwinska, Bogumila; Lopareva, Elena; Lupulescu, Emilia; Mentis, Andreas; Mihneva, Zefira; Mosquera, Maria M.; Muscat, Mark; Naumova, M.A.; Nedeljkovic, Jasminka; Nekrasova, Ljubov S.; Magurano, Fabio; Fortuna, Claudia; Rebelo de Andrade, Helena; Richard, Jean-Luc; Robo, Alma; Rota, Paul A.; Samoilovich, Elena O.; Sarv, Inna; Semeiko, Galina V.; Shugayev, Nazim; Utegenova, Elmira S.; van Binnendijk, Rob; Vinner, Lasse; Waku-Kouomou, Diane; Wild, T. Fabian; Brown, David W.G.; Mankertz, Annette; Muller, Claude P.; Mulders, Mick N.

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

High Genetic Diversity of Measles Virus, World Health Organization European Region, 2005–2006

Published Date:

Jan 2008

Source:

Emerg Infect Dis. 14(1):107-114.

[PDF-429.40 KB]

Details:

Personal Authors:

Kremer, Jacques R. ; Brown, Kevin E. ; Jin, Li ; Santibanez, Sabine ; Shulga, Sergey V. ; ... More ▼

Keywords:

[+]

Description:

During 2005-2006, nine measles virus (MV) genotypes were identified throughout the World Health Organization European Region. All major epidemics were associated with genotypes D4, D6, and B3. Other genotypes (B2, D5, D8, D9, G2, and H1) were only found in limited numbers of cases after importation from other continents. The genetic diversity of endemic D6 strains was low; genotypes C2 and D7, circulating in Europe until recent years, were no longer identified. The transmission chains of several indigenous MV strains may thus have been interrupted by enhanced vaccination. However, multiple importations from Africa and Asia and virus introduction into highly mobile and unvaccinated communities caused a massive spread of D4 and B3 strains throughout much of the region. Thus, despite the reduction of endemic MV circulation, importation of MV from other continents caused prolonged circulation and large outbreaks after their introduction into unvaccinated and highly mobile communities.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

	07-0778-F1.gif	image/gif
	07-0778-F1.jpg	image/jpeg
	07-0778-F2.gif	image/gif
	07-0778-F2.jpg	image/jpeg
	07-0778-F3.gif	image/gif
	07-0778-F3.jpg	image/jpeg
	07-0778-F4.gif	image/gif
	07-0778-F4.jpg	image/jpeg

No Related Documents.

You May Also Like:

Spread of Measles Virus D4-Hamburg, Europe, 2008–2011

Personal Author:

Mankertz, Annette; Mihneva, Zefira; Gold, Hermann; Baumgarte, Sigrid; Baillot, Armin; Helble, Rudolph; Roggendorf, Hedwig; Bosevska, Golubinka; Nedeljkovic, Jasminka; Makowka, Agata; Hutse, Veronik; Holzmann, Heidemarie; Aberle, Stefan W.; Cordey, Samuel; Necula, Gheorghe; Mentis, Andreas; Korukluoğlu, Gulay; Carr, Michael; Brown, Kevin E.; Hübschen, Judith M.; Muller, Claude P.; Mulders, Mick N.; Santibanez, Sabine;

Published:

Aug 2011

Source:

Emerg Infect Dis. 17(8):1396-1401.

Description:

A new strain of measles virus, D4-Hamburg, was imported from London to Hamburg in December 2008 and subsequently spread to Bulgaria, where an outbreak of >24,300 cases was observed. We analyzed spread of the virus to demonstrate the importance of add...

File Type:

[PDF - 256.36 KB]
Measles Virus Strain Diversity, Nigeria and Democratic Republic of the Congo

Personal Author:

Kremer, Jacques R.; Nkwembe, Edith; Oyefolu, Akeeb O. Bola; Smit, Sheilagh B.; Pukuta, Elisabeth; Omilabu, Sunday A.; Adu, Festus D.; Tamfum, Jean-Jacques Muyembe; Muller, Claude P.;

Published:

Nov 2010

Source:

Emerg Infect Dis. 16(11):1724-1730.

Description:

We investigated the genetic diversity of measles virus (MV) in Nigeria (2004-2005) and the Democratic Republic of the Congo (DRC) (2002-2006). Genotype B3 strains circulating in Kinshasa, DRC, in 2002-2003 were fully replaced by genotype B2 in 2004 a...

File Type:

[PDF - 300.29 KB]
Molecular Epidemiology of Measles Viruses in the United States, 1997–2001

Personal Author:

Rota, Paul A.; Liffick, Stephanie L.; Rota, Jennifer S.; Katz, Russell S.; Redd, Susan; Papania, Mark; Bellini, William J.;

Published:

Sep 2002

Source:

Emerg Infect Dis. 8(9):902-908.

Description:

From 1997 to 2001, sequence data from 55 clinical specimens were obtained from confirmed measles cases in the United States, representing 21 outbreaks and 34 sporadic cases. Sequence analysis indicated the presence of 11 of the recognized genotypes. ...

File Type:

[PDF - 244.15 KB]
Wild-Type Measles Viruses with Non-Standard Genome Lengths

Personal Author:

Bankamp, Bettina; Liu, Chunyu; Rivailler, Pierre; Bera, Jayati; Shrivastava, Susmita; Kirkness, Ewen F.; Bellini, William J.; Rota, Paul A.;

Published:

Apr 18 2014

Source:

PLoS One. 2014; 9(4).

Description:

The length of the single stranded, negative sense RNA genome of measles virus (MeV) is highly conserved at 15,894 nucleotides (nt). MeVs can be grouped into 24 genotypes based on the highly variable 450 nucleotides coding for the carboxyl-terminus of...

File Type:

[PDF - 2.66 MB]
Genetic Homogeneity of Measles Viruses Associated with a Measles Outbreak, São Paulo, Brazil, 1997

Personal Author:

Oliveira, Maria I.; Rota, Paul A.; Curti, Suely P.; Figueiredo, Cristina A.; Afonso, Ana M. S.; Theobaldo, Marcia; Souza, Luiza T.M.; Liffick, Stephanie L.; Bellini, William J.; Moraes, Jose C.; Stevien, Klaus E.; Durigon, Edison L.;

Published:

Aug 2002

Source:

Emerg Infect Dis. 8(8):808-813.

Description:

During a resurgence of measles in São Paulo, Brazil, in 1997, >40,000 cases (peak incidence rate of 246/100,000 inhabitants) and 42 measles-related deaths were reported. Reverse transcriptase-polymerase chain reaction and nucleotide sequencing were ...

File Type:

[PDF - 188.16 KB]