Detection of Group 1 Coronaviruses in Bats in North America

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Dominguez, Samuel R. ; O’Shea, Thomas J. ; Oko, Lauren M. ; Holmes, Kathryn V.
• Description:
  The epidemic of severe acute respiratory syndrome (SARS) was caused by a newly emerged coronavirus (SARS-CoV). Bats of several species in southern People's Republic of China harbor SARS-like CoVs and may be reservoir hosts for them. To determine whether bats in North America also harbor coronaviruses, we used reverse transcription-PCR to detect coronavirus RNA in bats. We found coronavirus RNA in 6 of 28 fecal specimens from bats of 2 of 7 species tested. The prevalence of viral RNA shedding was high: 17% in Eptesicus fuscus and 50% in Myotis occultus. Sequence analysis of a 440-bp amplicon in gene 1b showed that these Rocky Mountain bat coronaviruses formed 3 clusters in phylogenetic group 1 that were distinct from group 1 coronaviruses of Asian bats. Because of the potential for bat coronaviruses to cause disease in humans and animals, further surveillance and characterization of bat coronaviruses in North America are needed.
• Subjects:
  Animals Base Sequence Chiroptera Coronavirus Infections Phylogeny Research
• Source:
  Emerg Infect Dis. 13(9):1295-1300.
• Document Type:
  Journal Article
• Place as Subject:
  North America
• Location:
  North America
• Volume:
  13
• Issue:
  9
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:b1c71af3b4a492dee3d55d8e07e869af8be16a10cfa5e17884423d5d7f5cc104
• Download URL:
  https://stacks.cdc.gov/view/cdc/16824/cdc_16824_DS1.pdf
• File Type:
  [PDF - 285.92 KB ]