Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Siddiqui, M. Ruby ; Edmunds, W. John
Siddiqui, M. Ruby ; Edmunds, W. John Less -
Description:
A decision analytical model was developed to investigate the cost-effectiveness of stockpiling antiviral (AV) drugs for a potential influenza pandemic in the United Kingdom and the possible role of near-patient testing in conserving AV drug stocks. Under base-case assumptions (including a fixed stockpile that was smaller than the clinical attack rate), the treat-only option (treating all symptomatic patients with AV drugs) would be considered cost-effective ( pound1,900- pound13,700 per quality-adjusted life year [QALY] gained, depending on the fatality scenario), compared with no intervention (nonintervention but management of cases as they arise). The test-treat option (testing all symptomatic patients but treating those with positive tests results only) would result in moderate gains in QALYs over the treat-only option but at relatively large additional costs. Stockpiling sufficient AV drugs (but not near-patient tests) to treat all patients with clinical cases would be cost-effective, provided AV drugs are effective at preventing deaths from pandemic influenza.
Subject:
[+]
Antiviral Agents Cost-Benefit Analysis Decision Support Techniques Disease Outbreaks Health Care Costs Humans Influenza, Human Quality-Adjusted Life Years Sensitivity And Specificity
Source:
Emerg Infect Dis. 14(2):267-274.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:c13f726346765af1ae914243d66a4b1aa3d78eddb43c474bdcebd6ab1c82265a
Download URL:
https://stacks.cdc.gov/view/cdc/16819/cdc_16819_DS1.pdf
File Type:

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