Little Evidence for Genetic Susceptibility to Influenza A (H5N1) from Family Clustering Data

Pitzer, Virginia E.; Olsen, Sonja J.; Bergstrom, Carl T.; Dowell, Scott F.; Lipsitch, Marc

i

Little Evidence for Genetic Susceptibility to Influenza A (H5N1) from Family Clustering Data

Supporting Files Public Domain

Jul 2007
By Pitzer, Virginia E. ; Olsen, Sonja J. ; Bergstrom, Carl T. ; ...

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Pitzer, Virginia E. ; Olsen, Sonja J. ; Bergstrom, Carl T. ; Dowell, Scott F. ; Lipsitch, Marc
Description:

The apparent clustering of human cases of influenza A (H5N1) among blood relatives has been considered as evidence of genetic variation in susceptibility. We show that, by chance alone, a high proportion of clusters are expected to be limited to blood relatives when infection is a rare event.
Subjects:

Avian Influenza Child Cluster Analysis Disease Clustering, Dispatch Disease Susceptibility Dispatch Genetic Predisposition To Disease Genetic Susceptibility Genetic Variation Humans Influenza, Human Influenza A Virus, H5N1 Subtype Models, Binomial Models, Genetic
Source:

Emerg Infect Dis. 13(7):1074-1076.
Document Type:

Journal Article
Volume:

13
Issue:

7
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:d9dc1d0cf877019628b1c3311b931937ffb83ba940d858a7ea0431940210b892
Download URL:

https://stacks.cdc.gov/view/cdc/16646/cdc_16646_DS1.pdf
File Type:

[PDF - 432.93 KB ]

ON THIS PAGE

Details Supporting Files

CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.

As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.