Epidemiology of Streptococcus dysgalactiae subsp. equisimilis in Tropical Communities, Northern Australia

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  McDonald, Malcolm ; Towers, Rebecca J. ; Andrews, Ross M. ; Carapetis, Jonathan R. ; Currie, Bart J.
• Description:
  Streptococcus dysgalactiae subsp. equisimilis (groups C and G streptococci [GCS/GGS]) is an increasingly recognized human pathogen, although it may follow indirect pathways. Prospective surveillance of selected households in 3 remote Aboriginal communities in Australia provided 337 GCS/GGS isolates that were emm sequence-typed. Lancefield group C isolates (GCS) were localized to specific households and group G isolates (GGS) were more evenly distributed. GCS/GGS was more frequently recovered from the throat than group A streptococci (GAS [S. pyogenes]) but rarely recovered from skin sores, and then only with Staphylococcus aureus or GAS. Symptomatic GGS/GGC pharyngitis was also rare. Specific emm sequence types of GCS/GGS did not appear to cycle through the communities (sequential strain replacement) in a manner suggesting acquisition of type-specific immunity. These communities already have high levels of streptococcal and poststreptococcal disease. GCS/GGS may increase in importance as it acquires key virulence factors from GAS by lateral gene transfer.
• Subjects:
  Aboriginal Australian Adolescent Australia Child Emm Sequence Typing Group C Streptococci Group G Streptococci Humans Native Hawaiian Or Other Pacific Islander Pharyngitis Pharynx Population Surveillance Prospective Studies Pyoderma Research Rheumatic Fever Rheumatic Heart Disease S. Pyogenes Skin Streptococcal Infections Streptococcus Streptococcus Dysgalactiae Subsp. Equisimilis Tropical Climate

  More +
• Source:
  Emerg Infect Dis. 13(11):1694-1700.
• Document Type:
  Journal Article
• Volume:
  13
• Issue:
  11
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:a94c534b687ece7f8c9e75fe4dc503363d1b9be1d8dc2e7afdba1c41040d97ca
• Download URL:
  https://stacks.cdc.gov/view/cdc/16565/cdc_16565_DS1.pdf
• File Type:
  [PDF - 298.43 KB ]