CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.
As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.
i
West Nile Virus Viremia in Eastern Chipmunks (Tamias striatus) Sufficient for Infecting Different Mosquitoes
-
Jun 2007
-
-
Source: Emerg Infect Dis. 13(6):831-837.
[PDF-333.76 KB]
Details:
-
Alternative Title:Emerg Infect Dis
-
Personal Author:
-
Description:In eastern chipmunks (Tamias striatus) inoculated intramuscularly with 101.5 to 105.7 PFU of West Nile virus (WNV), serum titers developed sufficient to infect Aedes triseriatus (Say), Ae. vexans (Meigen), and Culex pipiens (L.). Mean titers (95% confidence interval) of 8 chipmunks were 103.9(3.3-4.5), 106.7(6.4-7.0), and 105.8(4.1-7.5) PFU/mL on days 1-3 postinoculation (p.i.) and 105.8 PFU/mL in 1 chipmunk on day 4 p.i. Mean estimated days that WNV titers were >104.8 and >105.6 were 1.7 (1.1-2.3) and 1.4 (1.0-1.6). The longest period of viremia >104.8 PFU/mL was 3-4 days. WNV antigen was detected in the small intestine of 2 chipmunks and the kidneys of 4 chipmunks by immunohistochemistry. WNV also was detected in urine, saliva, and feces of some chipmunks. These data suggest chipmunks might play a role in enzootic WNV cycles and be an amplifying host for mosquitoes that could infect humans.
-
Subjects:
-
Source:
-
Document Type:
-
Volume:13
-
Issue:6
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type:
